(溴甲基)环丁烷

(溴甲基)环丁烷结构式
(溴甲基)环丁烷结构式
品牌特惠专场
常用名 (溴甲基)环丁烷 英文名 Cyclobutylmethyl bromide
CAS号 17247-58-4 分子量 149.029
密度 1.4±0.1 g/cm3 沸点 124.0±8.0 °C at 760 mmHg
分子式 C5H9Br 熔点 N/A
MSDS 中文版 美版 闪点 43.9±13.6 °C
符号 GHS02 GHS07
GHS02, GHS07
信号词 Warning

Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors.

J. Med. Chem. 53(1) , 402-18, (2010)

The phenolic group of the potent mu and kappa opioid morphinan agonist/antagonists cyclorphan and butorphan was replaced by phenylamino and benzylamino groups including compounds with para-substituents in the benzene ring. These compounds are highly potent mu...

Function-oriented biosynthesis of beta-lactone proteasome inhibitors in Salinispora tropica.

J. Med. Chem. 52(19) , 6163-7, (2009)

The natural proteasome inhibitor salinosporamide A from the marine bacterium Salinispora tropica is a promising drug candidate for the treatment of multiple myeloma and mantle cell lymphoma. Using a comprehensive approach that combined chemical synthesis with...

Replacement surgery with unnatural amino acids in the lock-and-key joint of glutathione transferase subunits.

Chem. Biol. 13(9) , 929-36, (2006)

Proteins contain amino acid residues essential to structure and function. Ribosomal protein synthesis is typically limited to the 20 amino acids of the genetic code, but posttranslational chemical modifications can greatly expand the diversity of side chain f...

10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors.

J. Med. Chem. 47 , 165, (2004)

A series of 10-ketomorphinan analogues were synthesized, and their binding affinity at all three opioid receptors was investigated. In most cases, high affinity at micro and kappa receptors, and lower affinity at delta receptor was observed, resulting in good...

Photochemical synthesis and antimicrobial studies of new chromen-4-one based vinyl ethers. Yusuf M, et al.

Arabian Journal of Chemistry , (2013)

Cyclopropylmethyl-and cyclobutylmethyllithium by an arene-catalyzed lithiation. Stability and reactivity. Peñafiel I, et al.

Tetrahedron 66(16) , 2928-35, (2010)