二苯基碘鎓六氟磷酸盐

二苯基碘鎓六氟磷酸盐结构式
二苯基碘鎓六氟磷酸盐结构式
品牌特惠专场
常用名 二苯基碘鎓六氟磷酸盐 英文名 Diphenyliodonium hexafluorophosphate
CAS号 58109-40-3 分子量 426.07600
密度 N/A 沸点 N/A
分子式 C12H10F6IP 熔点 140-144 °C(lit.)
MSDS 中文版 美版 闪点 N/A
符号 GHS05
GHS05
信号词 Danger

Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase.

J. Neuroinflammation 9 , 32, (2012)

Both (-) and (+)-naloxone attenuate inflammation-mediated neurodegeneration by inhibition of microglial activation through superoxide reduction in an opioid receptor-independent manner. Multiple lines of evidence have documented a pivotal role of overactivate...

Unforeseen decreases in dissolved oxygen levels affect tube formation kinetics in collagen gels.

Am. J. Physiol. Cell Physiol. 301(2) , C431-40, (2011)

The availability of oxygen (O(2)) is a critical parameter affecting vascular tube formation. In this study, we hypothesize that dissolved oxygen (DO) levels in collagen gels change during the three-dimensional (3D) culture of human umbilical vein endothelial ...

Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes.

PLoS ONE 7(4) , e34904, (2012)

In obesity, there is an increase in reactive oxygen species (ROS) within adipose tissue caused by increases in inflammation and overnutrition. Hormone sensitive lipase (HSL) is part of the canonical lipolytic pathway and critical for complete lipolysis. This ...

NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation.

Parkinsonism Relat. Disord. 13 Suppl 3 , S316-20, (2007)

In this paper we report that diphenyliodonium (DPI), a NADPH oxidase inhibitor, shows potent anti-inflammatory and neuroprotective effects at femtomolar concentrations (10(-13) to 10(-14) M) in primary midbrain cultures. Mechanistic studies revealed that DPI-...

Serum amyloid A induces reactive oxygen species (ROS) production and proliferation of fibroblast.

Clin. Exp. Immunol. 163(3) , 362-7, (2011)

Serum amyloid A (SAA) levels are elevated highly in acute phase response and elevated slightly and persistently in chronic diseases such as rheumatoid arthritis and diabetes. Given that fibroblasts exert profound effects on progression of inflammatory chronic...

Myocardial autophagy after severe burn in rats.

PLoS ONE 7(6) , e39488, (2012)

Autophagy plays a major role in myocardial ischemia and hypoxia injury. The present study investigated the effects of autophagy on cardiac dysfunction in rats after severe burn.Protein expression of the autophagy markers LC3 and Beclin 1 were determined at 0,...

Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors.

Bioorg. Med. Chem. Lett. 19 , 972-5, (2009)

Plasmodium falciparum NDH2 (pfNDH2) is a non-proton pumping, rotenone-insensitive alternative enzyme to the multi-subunit NADH:ubiquinone oxidoreductases (Complex I) of many other eukaryotes. Recombinantly expressed pfNDH2 prefers coenzyme CoQ(0) as an accept...

Effect of initiator on photopolymerization of acidic, aqueous dental model adhesives.

J. Biomed. Mater. Res. A 90(4) , 1120-7, (2009)

This study evaluated different initiator systems in self-etching model adhesives, in which camphorquinone (CQ) or [3-(3,4-dimethyl-9-oxo-9H-thioxanthen-2-yloxy)-2-hydroxylpropy] trimethylammonium chloride (QTX) was employed as a photoinitiator (dye). N-phenyl...

Co-treatment with hepatocyte growth factor and TGF-beta1 enhances migration of HaCaT cells through NADPH oxidase-dependent ROS generation.

Exp. Mol. Med. 42(4) , 270-9, (2010)

Wound healing requires re-epithelialization from the wound margin through keratinocyte proliferation and migration, and some growth factors are known to influence this process. In the present study, we found that the co-treatment with hepatocyte growth factor...

Effect of thymol or diphenyliodonium chloride on performance, gut fermentation characteristics, and campylobacter colonization in growing swine.

J. Food Prot. 75(4) , 758-61, (2012)

Food producing animals can be reservoirs of Campylobacter, a leading bacterial cause of human foodborne illness. Campylobacter spp. utilize amino acids as major carbon and energy substrates, a process that can be inhibited by thymol and diphenyliodonium chlor...