钙离子载体 III
钙离子载体 III结构式
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常用名 | 钙离子载体 III | 英文名 | Calcimycin |
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| CAS号 | 52665-69-7 | 分子量 | 523.621 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 710.3±55.0 °C at 760 mmHg | |
| 分子式 | C29H37N3O6 | 熔点 | 187-190 °C | |
| MSDS | 美版 | 闪点 | 383.4±31.5 °C |
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[Characterisation of enucleated cells apoptosis: human platelets and erythrocytes].
Ross. Fiziol. Zh. Im. I. M. Sechenova 99(1) , 92-110, (2013) Apoptosis is a common mechanism of programmed cell death in virtually all nucleated cells. In spite of the fact that platelets and erythrocytes are the only enucleated cells in mammals they contain most of the apoptosis machinery of other cells and undergo si... |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Potent trypanocidal curcumin analogs bearing a monoenone linker motif act on trypanosoma brucei by forming an adduct with trypanothione.
Mol. Pharmacol. 87(3) , 451-64, (2015) We have previously reported that curcumin analogs with a C7 linker bearing a C4-C5 olefinic linker with a single keto group at C3 (enone linker) display midnanomolar activity against the bloodstream form of Trypanosoma brucei. However, no clear indication of ... |
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Immunoprevention of chemical carcinogenesis through early recognition of oncogene mutations.
J. Immunol. 194(6) , 2683-95, (2015) Prevention of tumors induced by environmental carcinogens has not been achieved. Skin tumors produced by polyaromatic hydrocarbons, such as 7,12-dimethylbenz(a)anthracene (DMBA), often harbor an H-ras point mutation, suggesting that it is a poor target for ea... |
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Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nat. Chem. Biol. 5 , 765-71, (2009) Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279... |
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An insufficient increase of cytosolic free calcium level results postovulatory aging-induced abortive spontaneous egg activation in rat.
J. Assist. Reprod. Genet. 30(1) , 117-23, (2013) The present study was aimed to find out whether postovulatory aging-induced abortive spontaneous egg activation (SEA) is due to insufficient increase of cytosolic free Ca(2+) level.Immature female rats (22-24 days old) were subjected to superovulation inducti... |
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Cathelicidin peptide LL-37 increases UVB-triggered inflammasome activation: possible implications for rosacea.
J. Dermatol. Sci. 76(3) , 173-9, (2014) In patients with rosacea, environmental stressors, especially UVB radiation, trigger disease flares that are characterized by inflammation and vascular hyperactivity. An altered innate immune detection and response system, modulated to a large extent by the a... |
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Mutasynthesis of pyrrole spiroketal compound using calcimycin 3-hydroxy anthranilic acid biosynthetic mutant.
Appl. Microbiol. Biotechnol. 97(18) , 8183-91, (2013) The five-membered aromatic nitrogen heterocyclic pyrrole ring is a building block for a wide variety of natural products. Aiming at generating new pyrrole-containing derivatives as well as to identify new candidates that may be of value in designing new antic... |
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Morphological alterations of all stages of spermatogenesis and acrosome reaction in Chinese mitten crab Eriocheir sinensis.
Cell Tissue Res. 360 , 401-12, (2015) The Chinese mitten crab (Eriocheir sinensis) is a seasonally breeding species and its reproductive system comprises paired symmetrical structures: testes, vasa deferentia, seminal vesicles, accessory glands and ejaculatory ducts. Histological examination of t... |
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SNAP23 Regulates Endothelial Exocytosis of von Willebrand Factor.
PLoS ONE 10 , e0118737, (2015) Endothelial exocytosis regulates vascular thrombosis and inflammation. The trafficking and release of endothelial vesicles is mediated by SNARE (Soluble NSF Attachment protein REceptors) molecules, but the exact identity of endothelial SNAREs has been unclear... |