N,N-二甲基苯甲酰胺结构式
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常用名 | N,N-二甲基苯甲酰胺 | 英文名 | 1N1&VR |
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| CAS号 | 611-74-5 | 分子量 | 149.190 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 256.1±9.0 °C at 760 mmHg | |
| 分子式 | C9H11NO | 熔点 | 43-45 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 111.9±9.9 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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The formation and metabolism of N-hydroxymethyl compounds--III. The metabolic conversion of N-methyl and N,N,-dimethylbenzamides to N-hydroxymethyl compounds.
Biochem. Pharmacol. 32(11) , 1773-81, (1983) The stability of metabolically-generated N-(hydroxymethyl) compounds was investigated using a series of N-methylbenzamides as model substrates. N-(Hydroxymethyl)-benzamide was characterized as a major metabolite of N-methylbenzamide in vitro, and was also ide... |
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Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs.
J. Control. Release 152(1) , 13-20, (2011) Polymer micelles have been used widely for delivery of poorly water-soluble drugs. Such drug delivery, however, has been based primarily on hydrophobic interactions. For better drug loading and improved stability, hydrotropic polymer micelles were used. To de... |
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Hydrotropic solubilization of poorly water-soluble drugs.
J. Pharm. Sci. 99(9) , 3953-65, (2010) The solubilizing ability of two aromatic hydrotropes, N,N-diethylnicotinamide (DENA) and N,N-dimethylbenzamide (DMBA), was investigated using a set of 13 poorly soluble, structurally diverse drugs. The number of aromatic rings in the solute molecule has a ver... |
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Kinetic deuterium isotope effects on the N-demethylation of tertiary amides by cytochrome P-450.
J. Biol. Chem. 265(21) , 12349-55, (1990) Liver microsomal cytochrome P-450 readily N-dealkylates N,N-dimethylamides. N-Methyl-N-hydroxymethyl amides were isolated as intermediates and characterized by gas chromatography-mass spectrometry as their trimethylsilyl ethers. Intramolecular kinetic deuteri... |
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Reactions of ethyl-and phenyllanthanide s complexes with n, n-dimethylbenzamide and benzaldehyde. Yokoo K, et al.
Polyhedron 2(10) , 1101-02, (1983)
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Deuterium exchange labelling of substituted aromatics using [IrH2 (Me2CO) 2 (PPh3)2] BF4. Heys JR, et al.
J. Labelled Comp. Radiopharm. 33(5) , 431-8, (1993)
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