4-(氟磺酰)苯甲酸
4-(氟磺酰)苯甲酸结构式
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常用名 | 4-(氟磺酰)苯甲酸 | 英文名 | 4-(fluorosulphonyl)benzoic acid |
|---|---|---|---|---|
| CAS号 | 455-26-5 | 分子量 | 204.17600 | |
| 密度 | 1.538g/cm3 | 沸点 | 335.3ºC at 760mmHg | |
| 分子式 | C7H5FO4S | 熔点 | 272-273ºC(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 156.6ºC | |
| 符号 |
GHS05 |
信号词 | Danger |
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Affinity labeling of glutathione S-transferase, isozyme 4-4, by 4-(fluorosulfonyl)benzoic acid reveals Tyr115 to be an important determinant of xenobiotic substrate specificity.
Biochemistry 32(48) , 13002-11, (1993) Incubation of 4-(fluorosulfonyl)benzoic acid (4-FSB), a xenobiotic substrate analogue, with the 4-4 isozyme of rat liver glutathione S-transferase at pH 7.5 and 25 degrees C results in a time-dependent inactivation of the enzyme. The rate of inactivation exhi... |
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Affinity labeling of pig lung glutathione S-transferase pi by 4-(fluorosulfonyl)benzoic acid.
Arch. Biochem. Biophys. 364 , 107-114, (1999) The compound 4-(fluorosulfonyl)benzoic acid (4-FSB) functions as an affinity label of the dimeric pig lung pi class glutathione S-transferase yielding a completely inactive enzyme. Protection against inactivation is provided by glutathione-based ligands, sugg... |
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Anti-sulfonylbenzoate antibodies as a tool for the detection of nucleotide-binding proteins for functional proteomics.
J. Proteome Res. 3(6) , 1184-90, (2004) Proteins that bind ATP and GTP are important cellular components. We developed an immunological approach to selectively tag nucleotide-binding proteins based on the use of 5'-[4-(fluorosulfonyl)benzoyl]adenosine and 5'-[4-(fluorosulfonyl)benzoyl]guanosine aff... |
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Tyrosine 8 contributes to catalysis but is not required for activity of rat liver glutathione S-transferase, 1-1.
Protein Sci. 5(6) , 1032-42, (1996) Reaction of rat liver glutathione S-transferase, isozyme 1-1, with 4-(fluorosulfonyl)benzoic acid (4-FSB), a xenobiotic substrate analogue, results in a time-dependent inactivation of the enzyme to a final value of 35% of its original activity when assayed at... |