马来酸三甲丙咪嗪

J. Pharm. Biomed. Anal. 94 , 111-7, (2014)

A rapid, accurate, precise and versatile analytical method was developed for the detection and quantification of water in solid active pharmaceutical ingredients (APIs). The headspace gas chromatography (HSGC) method utilized an ionic liquid (IL) based open t...

Cochrane Database Syst. Rev. 9 , CD003853, (2012)

This is an update of a Cochrane review first published in The Cochrane Library in Issue 4, 2006 and previously updated in 2009.Tinnitus is described as the perception of sound or noise in the absence of real acoustic stimulation. It has been compared with chr...

Am. Fam. Physician 84(9) , 1-2, (2011)

Talanta 83(5) , 1376-80, (2011)

The tricyclic antidepressants (TCA) imipramine (Imi) and trimipramine (Tri) were successfully analyzed by capillary electrophoresis (CE) coupling with Tris(2,2-bipyridyl) ruthenium(II)-based (Ru(bpy)(3)(2+)) end-column electrochemiluminescence (ECL) detection...

Drug Metab. Dispos. 38(5) , 863-70, (2010)

The role of human UDP glucuronosyltransferase (UGT) 2B10 in the N-glucuronidation of a number of tricyclic antidepressants was investigated and compared with that of UGT1A4 in both the Sf9 expressed system and human liver microsomes. The apparent K(m) (S(50))...

J. Forensic Leg. Med. 17(3) , 164-8, (2010)

In clinical medicine, plane radiography is used for detecting the remains of medications in the stomach in oral medication intoxication cases. Since postmortem computed tomography (CT), performed prior to autopsy, is currently intensively entering the forensi...

Psychopharmacology 217(2) , 289-95, (2011)

The antidepressant trimipramine shows an atypical pharmacological profile and its mechanism of action is still obscure.The present study investigated whether trimipramine and three of its metabolites interact with targets of other antidepressants, namely, the...

Psychiatry Res. 167(3) , 279-86, (2009)

Trimipramine is a sedating tricyclic antidepressant which is not only effective in the treatment of depression but also in primary insomnia. In contrast to most other antidepressants, trimipramine does not affect rapid eye movement sleep. In a large sample of...

J. Psychiatr. Res. 42(7) , 578-86, (2008)

The intake of antidepressants is often accompanied by weight gain. Antidepressants may influence lipid and carbohydrate metabolism that can result in metabolic changes and obesity. We investigated the effect of citalopram and trimipramine on interstitial glyc...

Pharmacol. Biochem. Behav. 83(4) , 592-7, (2006)

The present study was designed to investigate the involvement of endogenous opioid systems in the antinociception induced by the antidepressant drugs, desipramine and trimipramine. For this purpose, the antinociceptive effects of desipramine (7.5 and 15.0 mg/...