马来酸三甲丙咪嗪

马来酸三甲丙咪嗪结构式
马来酸三甲丙咪嗪结构式
品牌特惠专场
常用名 马来酸三甲丙咪嗪 英文名 Trimipramine maleate
CAS号 521-78-8 分子量 410.506
密度 1.029g/cm3 沸点 411.8ºC at 760mmHg
分子式 C24H30N2O4 熔点 141-143ºC
MSDS 中文版 美版 闪点 183.3ºC
符号 GHS07 GHS08
GHS07, GHS08
信号词 Warning

Water determination in active pharmaceutical ingredients using ionic liquid headspace gas chromatography and two different detection protocols.

J. Pharm. Biomed. Anal. 94 , 111-7, (2014)

A rapid, accurate, precise and versatile analytical method was developed for the detection and quantification of water in solid active pharmaceutical ingredients (APIs). The headspace gas chromatography (HSGC) method utilized an ionic liquid (IL) based open t...

Antidepressants for patients with tinnitus.

Cochrane Database Syst. Rev. 9 , CD003853, (2012)

This is an update of a Cochrane review first published in The Cochrane Library in Issue 4, 2006 and previously updated in 2009.Tinnitus is described as the perception of sound or noise in the absence of real acoustic stimulation. It has been compared with chr...

FPIN's clinical inquiries: Antidepressants for the treatment of insomnia in patients with depression.

Am. Fam. Physician 84(9) , 1-2, (2011)

Determination of imipramine and trimipramine by capillary electrophoresis with electrochemiluminescence detection.

Talanta 83(5) , 1376-80, (2011)

The tricyclic antidepressants (TCA) imipramine (Imi) and trimipramine (Tri) were successfully analyzed by capillary electrophoresis (CE) coupling with Tris(2,2-bipyridyl) ruthenium(II)-based (Ru(bpy)(3)(2+)) end-column electrochemiluminescence (ECL) detection...

Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.

Drug Metab. Dispos. 38(5) , 863-70, (2010)

The role of human UDP glucuronosyltransferase (UGT) 2B10 in the N-glucuronidation of a number of tricyclic antidepressants was investigated and compared with that of UGT1A4 in both the Sf9 expressed system and human liver microsomes. The apparent K(m) (S(50))...

Radiopaque stomach contents in postmortem CT in suicidal oral medication intoxication: report of three cases.

J. Forensic Leg. Med. 17(3) , 164-8, (2010)

In clinical medicine, plane radiography is used for detecting the remains of medications in the stomach in oral medication intoxication cases. Since postmortem computed tomography (CT), performed prior to autopsy, is currently intensively entering the forensi...

Inhibitory potencies of trimipramine and its main metabolites at human monoamine and organic cation transporters.

Psychopharmacology 217(2) , 289-95, (2011)

The antidepressant trimipramine shows an atypical pharmacological profile and its mechanism of action is still obscure.The present study investigated whether trimipramine and three of its metabolites interact with targets of other antidepressants, namely, the...

The effect of trimipramine on dream recall and dream emotions in depressive outpatients.

Psychiatry Res. 167(3) , 279-86, (2009)

Trimipramine is a sedating tricyclic antidepressant which is not only effective in the treatment of depression but also in primary insomnia. In contrast to most other antidepressants, trimipramine does not affect rapid eye movement sleep. In a large sample of...

Metabolism in adipose tissue in response to citalopram and trimipramine treatment--an in situ microdialysis study.

J. Psychiatr. Res. 42(7) , 578-86, (2008)

The intake of antidepressants is often accompanied by weight gain. Antidepressants may influence lipid and carbohydrate metabolism that can result in metabolic changes and obesity. We investigated the effect of citalopram and trimipramine on interstitial glyc...

The involvement of endogenous opioid mechanisms in the antinociceptive effects induced by antidepressant drugs, desipramine and trimipramine.

Pharmacol. Biochem. Behav. 83(4) , 592-7, (2006)

The present study was designed to investigate the involvement of endogenous opioid systems in the antinociception induced by the antidepressant drugs, desipramine and trimipramine. For this purpose, the antinociceptive effects of desipramine (7.5 and 15.0 mg/...