己内酰胺
己内酰胺结构式
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常用名 | 己内酰胺 | 英文名 | Caprolactam |
|---|---|---|---|---|
| CAS号 | 105-60-2 | 分子量 | 113.158 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 268 ºC | |
| 分子式 | C6H11NO | 熔点 | 68-71 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 152 ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Structure elucidation and quantification of impurities formed between 6-aminocaproic acid and the excipients citric acid and sorbitol in an oral solution using high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy.
J. Pharm. Biomed. Anal. 107 , 333-40, (2015) Concentrated solutions containing 6-aminocaproic acid and the excipients citric acid and sorbitol have been studied at temperatures of 50°C, 60°C, 70°C and 80°C as well as at 20°C. It has previously been reported that the commonly employed citric acid is a re... |
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A comparison of the effect of temperature and moisture on the solid dispersions: aging and crystallization.
Int. J. Pharm. 475(1-2) , 385-92, (2014) The purpose of this work was to compare the effect of temperature and relative humidity (RH) on the physical stability and dissolution of solid dispersions. Cinnarizine-Soluplus(®) solid dispersions (SDs) at three different drug loadings (10, 20 and 35 wt%) w... |
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Investigation of drug-polymer interaction in solid dispersions by vapour sorption methods.
Int. J. Pharm. 469(1) , 159-67, (2014) The objective of this study was to investigate the effect of different polymeric carriers in solid dispersions with an active pharmaceutical ingredient (API) on their water vapour sorption equilibria and the influence of the API-polymer interactions on the di... |
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Theoretical prediction of a phase diagram for solid dispersions.
Pharm. Res. 32(3) , 840-51, (2015) To predict the temperature-composition phase diagram of solid dispersions (SDs) through theoretical approaches using cinnarizine-Soluplus(®) SD as a model system and evaluate the predicted results.A complete phase diagram of cinnarizine-Soluplus(®) SD, includ... |
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Complete genome sequence of the caprolactam-degrading bacterium Pseudomonas mosselii SJ10 isolated from wastewater of a nylon 6 production plant.
J. Biotechnol. 192 Pt A , 263-4, (2015) Pseudomonas mosselii strain SJ10 is a caprolactam-degrading bacterium belonging to the class Gammaproteobacteria, which was isolated from wastewater of the nylon 6 producing Seongseo industrial complex in Daegu, Republic of Korea. Here, we report the complete... |
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Determination of caprolactam and residual vinyl caprolactam monomer in soluplus by mixed mode gel permeation chromatography.
J. Chromatogr. Sci. 52(5) , 413-7, (2014) Soluplus, a graft copolymer of polyethylene glycol, vinyl caprolactam and vinyl acetate, is designed to solubilize poorly soluble active pharmaceutical ingredients. A straightforward aqueous gel permeation chromatography method that exploits both size exclusi... |
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Biologic activity of epsilon-caprolactam.
Crit. Rev. Toxicol. 13(3) , 205-16, (1984) In general, this literature review indicates that epsilon-caprolactam has a relatively low toxicity to humans. This low-degree of toxicity is attributable in part to its rapid elimination as demonstrated by experimental studies on animals. Human studies are m... |
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Enantiospecific total synthesis of (-)-bengamide E.
Chem. Asian J. 8(2) , 488-93, (2013) Total synthesis of the polyhydroxy caprolactam amide natural product, bengamide E, is accomplished starting from tartaric acid. Key reactions in the synthesis include desymmetrization of the bis(dimethylamide) unit of tartaric acid, Zn(BH(4))(2)-mediated anti... |
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Mechanical, thermal and bioactive behaviors of polyamide 6/hydroxyapatite nanocomposites.
J. Nanosci. Nanotechnol. 11(12) , 10644-8, (2011) Polyamide-6 nanocomposites filled with different hydroxyapatite nanorod contents were injection molded. The thermal and tensile properties as well as bioactivity of such nanocomposties were investigated. The results showed that the thermal stabilities of poly... |
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A study of slippage of various knot configurations.
Eye (Lond.) 26(11) , 1491-3, (2012)
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