氯乙酰氯

一般危化品
氯乙酰氯结构式
氯乙酰氯结构式
常用名 氯乙酰氯 英文名 Chloroacetyl chloride
CAS号 79-04-9 分子量 112.943
密度 1.4±0.1 g/cm3 沸点 106.0±0.0 °C at 760 mmHg
分子式 C2H2Cl2O 熔点 −22 °C(lit.)
MSDS 中文版 美版 闪点 34.0±20.2 °C
符号 GHS05 GHS06 GHS08 GHS09
GHS05, GHS06, GHS08, GHS09
信号词 Danger

Comparative evaluation of Bis(thiosemicarbazone)- Biotin and Met-ac-TE3A for tumor imaging.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 153 , 566-71, (2015)

2,2',2″-(11-(2-((4-mercapto-1-methoxy-1-oxobutan-2-yl)amino)-2-oxoethyl)-1,4,8,11-tetraaza cyclotetradecane-1,4,8-triyl)triacetic acid, Met-ac-TE3A and (E)-N-methyl-2-((E)-3-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)hydrazi...

New hydrazines with sulphonamidic structure: synthesis,characterization and biological activity.

Rev. Med. Chir. Soc. Med. Nat. Iasi. 117(1) , 238-43, (2013)

Infections caused by bacterial species are common in immunocompromised patients and carry significant treatment costs and mortality. The emerging resistance of microorganisms to some synthetic antimicrobial agents makes it necessary to continue the research f...

Cysteine cyclic pyrrole-imidazole polyamide for sequence-specific recognition in the DNA minor groove.

J. Am. Chem. Soc. 133(46) , 18924-30, (2011)

Pyrrole-imidazole (PI) polyamides are small DNA-binding molecules that can recognize predetermined DNA sequences with high affinity and specificity. Hairpin PI polyamides have been studied intensively; however, cyclic PI polyamides have received less attentio...

[Hygienic standardization of monochloracetic acid chloranhydride in the air of the work area].

Gig. Tr. Prof. Zabol. (10) , 56-7, (1988)

[Preparation of aminated porous resin and for bilirubin adsorption].

Sheng Wu Gong Cheng Xue Bao 25(4) , 611-7, (2009)

Polystyrene microspheres (PS) were successfully prepared by suspension polymerization processes. Chloroacetylated polystyrene has been prepared by Friedel-Crafts acetylation of PS with chloroacetyl chloride. In this report, carcinogenic compound (chloromethyl...

[Three cases of acute chloroacetyl chloride poisoning].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 26(10) , 600, (2008)

[Heterogeneity of Rhodococcus opacus 1CP as a response to stress induced by chlorophenols].

Prikl. Biokhim. Mikrobiol. 41(5) , 541-6, (2005)

Dissociation of Rhodococcus opacus 1CP during culturing in different media (containing phenol and its monochlorinated derivatives as the sole source of carbon and energy) was studied. Three variants of strain 1CP (S1, S2, and R) differing in the morphology of...

Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene.

Chem. Biol. Interact. 95(3) , 227-44, (1995)

1,1-Dichloroethylene (DCE) requires cytochrome P450-catalyzed bioactivation to electrophilic metabolites (1,1-dichloroethylene oxide, 2-chloroacetyl chloride and 2,2-dichloroacetaldehyde) to exert its cytotoxic effects. In this investigation, we examined the ...

The use of a dendrimer-propranolol prodrug to bypass efflux transporters and enhance oral bioavailability.

J. Control. Release 95(3) , 447-53, (2004)

The aim of the study was to determine the effects on the transport of propranolol across monolayers of the human colon adenocarcinoma cell line, Caco-2, of forming a prodrug by conjugating to generation 3 (G3) and lauroyl-G3 PAMAM dendrimers. Propranolol is a...

Bioactivation of 1,1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes.

Drug Metab. Dispos. 32(9) , 1032-9, (2004)

1,1-Dichloroethylene (DCE) exposure to mice elicits lung toxicity that selectively targets bronchiolar Clara cells. The toxicity is mediated by DCE metabolites formed via cytochrome P450 metabolism. The primary metabolites formed are DCE epoxide, 2,2-dichloro...