4-氟-7-硝基-2,1,3-苯并氧杂恶二唑
4-氟-7-硝基-2,1,3-苯并氧杂恶二唑结构式
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常用名 | 4-氟-7-硝基-2,1,3-苯并氧杂恶二唑 | 英文名 | 4-Fluoro-7-nitrobenzofurazan |
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| CAS号 | 29270-56-2 | 分子量 | 183.097 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | 308.6±45.0 °C at 760 mmHg | |
| 分子式 | C6H2FN3O3 | 熔点 | 52-54 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 140.4±28.7 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Analysis of mono-, di- and oligosaccharides by CE using a two-stage derivatization method and LIF detection.
Electrophoresis 30(8) , 1399-405, (2009) A sensitive CE with LIF method has been developed for quantitative analysis of small carbohydrates. In this work, 17 carbohydrates including mono-, di- and oligosaccharides were simultaneously derivatized with 4-fluoro-7-nitrobenzofurazane (NBD-F) via a two-s... |
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Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.
Biochim. Biophys. Acta 1828(9) , 2152-63, (2013) Submillimolar concentrations of cytotoxic bile acids (BAs) induce cell death via apoptosis. On the other hand, several cytoprotective BAs were shown to prevent apoptosis in the same concentration range. Still, the mechanisms by which BAs trigger these opposit... |
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Evaluation of a microchip electrophoresis-mass spectrometry platform deploying a pressure-driven make-up flow.
J. Chromatogr. A. 1285 , 159-64, (2013) Integration of a pressure-driven make-up flow (MUF) into a microchip electrophoresis (MCE) platform in order to facilitate its coupling with electrospray ionization-mass spectrometric detection (ESI-MS) is described. In the glass/PDMS hybrid microchip, a MUF ... |
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Role of alphaPhe-291 residue in the phosphate-binding subdomain of catalytic sites of Escherichia coli ATP synthase.
Arch. Biochem. Biophys. 471(2) , 168-75, (2008) The role of alphaPhe-291 residue in phosphate binding by Escherichia coli F1F0-ATP synthase was examined. X-ray structures of bovine mitochondrial enzyme suggest that this residue resides in close proximity to the conserved betaR246 residue. Herein, we show t... |
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Rapid and validated fluorometric HPLC method for determination of gabapentin in human plasma and urine for clinical application.
J. Clin. Pharm. Ther. 37 , 89-94, (2012) A rapid derivatization and validated HPLC method for gabapentin in human plasma and urine is needed for clinical use. The objective of this study was to establish a rapid and validated analytical method for the determination of gabapentin in human plasma and ... |
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Improved determination of D-glucosamine hydrochloride in health foods by HPLC using 7-fluoro-4-nitrobenzo-2-oxa-l,3-diazole as a derivative.
J. Food Sci. 76(9) , N74-8, (2011) This article presents an improved method to detect D-glucosamine hydrochloride in health foods. A simple precolumn derivatization procedure with 7-flouro-4-nitrobenzo-2-oxa-1,3-diazole (NBD-F) reagent was employed. The separation of the derivatized D-glucosam... |
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Utilization of 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) for kinetic spectrophotometric assay of befunolol hydrochloride in its pharmaceutical formulation.
J. AOAC Int. 89(3) , 646-50, (2006) A simple, accurate, precise, and sensitive kinetic spectrophotometric method for determination of befunolol hydrochloride is described. The method is based on the formation of a colored product with 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) in methanol a... |
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Sensitive determination of 4-(4-bromophenyl)-4-hydroxypiperidine, a metabolite of bromperidol, in rat plasma by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole.
Biol. Pharm. Bull. 29(12) , 2479-82, (2006) The purpose of this study was to determine the level of 4-(4-bromophenyl)-4-hydroxypiperidine (BPHP), a bromperidol (BRO) metabolite, in rat plasma by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole... |
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A sensitive and rapid determination of ranitidine in human plasma by HPLC with fluorescence detection and its application for a pharmacokinetic study.
J. Chromatogr. Sci. 50(4) , 301-6, (2012) A novel precolumn derivatization reversed-phase high-performance liquid chromatography method with fluorescence detection is described for the determination of ranitidine in human plasma. The method was based on the reaction of ranitidine with 4-fluoro-7-nitr... |
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Rapid determination of amino acids in biological samples using a monolithic silica column.
Amino Acids 42(5) , 1897-902, (2012) A high-performance liquid chromatography method in which fluorescence detection is used for the simultaneous determination of 21 amino acids is proposed. Amino acids were derivatized with 4-fluoro-7-nitro-2,1,3-benzoxadiazole (NBD-F) and then separated on a m... |