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3-[(3-胆固醇氨丙基)二甲基氨基]-1-丙磺酸

3-[(3-胆固醇氨丙基)二甲基氨基]-1-丙磺酸结构式
3-[(3-胆固醇氨丙基)二甲基氨基]-1-丙磺酸结构式
品牌特惠专场
常用名 3-[(3-胆固醇氨丙基)二甲基氨基]-1-丙磺酸 英文名 CHAPS
CAS号 75621-03-3 分子量 614.877
密度 1.01 g/mL at 20ºC 沸点 N/A
分子式 C32H58N2O7S 熔点 156-158ºC
MSDS 中文版 闪点 N/A

Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation.

Biochem. Pharmacol. 90(3) , 288-96, (2014)

Inhibition of 17α-hydroxylase/17,20-lyase (CYP17), which dictates the proceeding of androgen biosynthesis, is recommended as an effective treatment for androgen-dependent diseases. However, androgen depletion by selective CYP17 inhibition is accompanied with ...

Endogenous fatty acids in olfactory hairs influence pheromone binding protein structure and function in Lymantria dispar.

Arch. Biochem. Biophys. 579 , 73-84, (2015)

The gypsy moth utilizes a pheromone, (7R,8S)-2-methyl-7,8-epoxyoctadecane, for mate location. The pheromone is detected by sensory hairs (sensilla) on the antennae of adult males. Sensilla contain the dendrites of olfactory neurons bathed in lymph, which cont...

A biophysical study on molecular physiology of the uncoupling proteins of the central nervous system.

Biosci. Rep. 35 , (2015)

Mitochondrial inner membrane uncoupling proteins (UCPs) facilitate transmembrane (TM) proton flux and consequently reduce the membrane potential and ATP production. It has been proposed that the three neuronal human UCPs (UCP2, UCP4 and UCP5) in the central n...

Heat Shock Protein member A2 forms a stable complex with angiotensin converting enzyme and protein disulfide isomerase A6 in human spermatozoa.

Mol. Hum. Reprod. 22 , 93-109, (2016)

Given the importance of the chaperone Heat Shock Protein A2 (HSPA2) in the regulation of male fertility, this study aimed to identify and characterize additional proteins that may rely on the activity of this chaperone in human spermatozoa.In view of the find...

Peroxiredoxin 6 Is a Crucial Factor in the Initial Step of Mitochondrial Clearance and Is Upstream of the PINK1-Parkin Pathway.

Antioxid. Redox Signal. 24 , 486-501, (2016)

PTEN-putative kinase 1 (PINK1)-Parkin-mediated mitophagy is crucial for the clearance of damaged mitochondria. However, the mechanisms underlying PINK1-Parkin-mediated mitophagy are not fully understood. The goal of this study is to identify new regulators an...

Identification of apolipoprotein C-I as a potential Wilms' tumor marker after excluding inflammatory factors.

Int. J. Mol. Sci. 15(9) , 16186-95, (2014)

Wilms' tumor is one of the most common malignant tumors observed in children, and its early diagnosis is important for late-stage treatment and prognosis. We previously screened and identified protein markers for Wilms' tumor; however, these markers lacked sp...

High-throughput screening method for lipases/esterases.

Methods Mol. Biol. 861 , 89-100, (2012)

High-throughput screening (HTS) methods for lipases and esterases are generally performed by using synthetic chromogenic substrates (e.g., p-nitrophenyl, resorufin, and umbelliferyl esters) which may be misleading since they are not their natural substrates (...

Stem and progenitor cell division kinetics during postnatal mouse mammary gland development.

Nat. Commun. 6 , 8487, (2015)

The cycling properties of mammary stem and progenitor cells is not well understood. To determine the division properties of these cells, we administered synthetic nucleosides for varying periods of time to mice at different stages of postnatal development and...

Morphological and proteomic analyses reveal that unsaturated guluronate oligosaccharide modulates multiple functional pathways in murine macrophage RAW264.7 cells.

Mar. Drugs 13 , 1798-818, (2015)

Alginate is a natural polysaccharide extracted from various species of marine brown algae. Alginate-derived guluronate oligosaccharide (GOS) obtained by enzymatic depolymerization has various pharmacological functions. Previous studies have demonstrated that ...

Type and composition of surfactants mediating gene transfection of polyethylenimine-coated liposomes.

Int. J. Nanomedicine 6 , 975-83, (2011)

The objective of this study was to compare the transfection efficiency of anionic liposomes coated with polyethylenimine (PEI) with that of PEI and Lipofectamine 2000(™) using the plasmid DNA encoding green fluorescent protein in a human hepatoma (Huh7) cell ...