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四乙基氯化铵

四乙基氯化铵结构式
四乙基氯化铵结构式
品牌特惠专场
常用名 四乙基氯化铵 英文名 Tetraethylammonium chloride
CAS号 56-34-8 分子量 165.704
密度 1.08 沸点 N/A
分子式 C8H20ClN 熔点 39°C
MSDS 中文版 美版 闪点 N/A

Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes.

Mol. Pharmacol. 82(6) , 1129-35, (2012)

Transient receptor potential vanilloid subtype 1 (TRPV1) channels are essential nociceptive integrators in primary afferent neurons. These nonselective cation channels are inhibited by local anesthetic compounds through an undefined mechanism. Here, we show t...

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ...

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.

Nature Chemistry 6(10) , 885-92, (2014)

Anion transporters based on small molecules have received attention as therapeutic agents because of their potential to disrupt cellular ion homeostasis. However, a direct correlation between a change in cellular chloride anion concentration and cytotoxicity ...

Caspase-dependent cell death-associated release of nucleosome and damage-associated molecular patterns.

Cell Death Dis. 5 , e1494, (2014)

Apoptosis, which is anti-inflammatory, and necrosis, which is pro-inflammatory, represent the extremes of the cell death spectrum. Cell death is complex and both apoptosis and necrosis can be observed in the same cells or tissues. Here, we introduce a novel c...

Vasorelaxant effects of 1-nitro-2-phenylethene in rat isolated aortic rings.

Vascul. Pharmacol. 63(2) , 55-62, (2014)

Previously, we showed that nitro-2-phenylethane is a vasorelaxant constituent of the essential oil of Aniba canelilla. Here, we investigated the mechanisms underlying the vascular effects of 1-nitro-2-phenylethene (NPe), a structural analog of 1-nitro-2-pheny...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened seven parasite lines for differences in responses to 1,279...

Differential role of ethylene and hydrogen peroxide in dark-induced stomatal closure.

Pak. J. Biol. Sci. 16(24) , 1991-6, (2013)

Regulation of stomatal aperture is crucial in terrestrial plants for controlling water loss and gaseous exchange with environment. While much is known of signaling for stomatal opening induced by blue light and the role of hormones, little is known about the ...

Cu nanoparticles electrodeposited at liquid-liquid interfaces: a highly efficient catalyst for the hydrogen evolution reaction.

Chemistry 21(12) , 4585-9, (2015)

The electrochemical deposition of Cu nanoparticles with an average diameter of approximately 25-35 nm has been reported at liquid-liquid interfaces by using the organic-phase electron-donor decamethylferrocene (DMFc). The electrodeposited Cu nanoparticles dis...

Effects of moderate static magnetic fields on the voltage-gated sodium and calcium channel currents in trigeminal ganglion neurons.

Electromagn. Biol. Med. 34 , 285-92, (2015)

To study the effects of static magnetic fields (SMF) on the electrophysiological properties of voltage-gated sodium and calcium channels on trigeminal ganglion (TRG) neurons.Acutely dissociated TRG neurons of neonatal SD rats were exposed to 125-mT and 12.5-m...

Relaxant effect of flavonoid naringenin on contractile activity of rat colonic smooth muscle.

J. Ethnopharmacol. 155(2) , 1177-83, (2014)

Disturbed gastrointestinal (GI) motility can be associated with smooth muscle abnormalities and dysfunction. Exploring innovative approaches that can modulate the disturbed colonic motility are of great importance for clinical therapeutics. Naringenin, a flav...