邻氨基苯酚

一般危化品
邻氨基苯酚结构式
邻氨基苯酚结构式
常用名 邻氨基苯酚 英文名 aminophenol
CAS号 95-55-6 分子量 109.126
密度 1.2±0.1 g/cm3 沸点 234.5±23.0 °C at 760 mmHg
分子式 C6H7NO 熔点 172 °C
MSDS 中文版 美版 闪点 95.6±22.6 °C
符号 GHS07 GHS08
GHS07, GHS08
信号词 Warning

The EpiOcular Eye Irritation Test (EIT) for hazard identification and labelling of eye irritating chemicals: protocol optimisation for solid materials and the results after extended shipment.

Altern. Lab. Anim. 43 , 101-27, (2015)

The 7th Amendment to the EU Cosmetics Directive and the EU REACH Regulation have reinforced the need for in vitro ocular test methods. Validated in vitro ocular toxicity tests that can predict the human response to chemicals, cosmetics and other consumer prod...

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspase activity by 50% (I50) and utilized these data to develop ...

Mechanistic studies of the tyrosinase-catalyzed oxidative cyclocondensation of 2-aminophenol to 2-aminophenoxazin-3-one.

Arch. Biochem. Biophys. 577-578 , 24-34, (2015)

Tyrosinase (EC 1.14.18.1) catalyzes the monophenolase and diphenolase reaction associated with vertebrate pigmentation and fruit/vegetable browning. Tyrosinase is an oxygen-dependent, dicopper enzyme that has three states: Emet, Eoxy, and Edeoxy. The diphenol...

IL-8 release from human neutrophils cultured with pro-haptenic chemical sensitizers.

Chem. Res. Toxicol. 25(10) , 2054-6, (2012)

Cytokine release from dendritic cells in vitro is a useful marker to discriminate between sensitizing and irritant haptenic chemicals. Unfortunately, pro-haptens, which gain reactivity following metabolic/auto activation, yield negative results. To overcome t...

2-Nitrophenol reduction promoted by S. putrefaciens 200 and biogenic ferrous iron: the role of different size-fractions of dissolved organic matter.

J. Hazard. Mater. 279 , 436-43, (2014)

The reduction of nitroaromatic compounds (listed as a priority pollutant) in natural subsurface environments typically coexists with dissimilatory reduction of iron oxides effected by dissolved organic matter (DOM). Investigating the impact of the DOM that in...

Synthesis, characterization and biological evaluation of Fe (III), Co (II), Ni(II), Cu(II), and Zn(II) complexes with tetradentate Schiff base ligand derived from protocatechualdehyde with 2-aminophenol.

Appl. Biochem. Biotechnol. 167(3) , 581-94, (2012)

Schiff base ligand (H(3)L) was prepared from the condensation reaction of protochatechualdehyde (3,4-dihydroxybenzaldhyde)with 2-amino phenol. From the direct reaction of the ligand (H(3)L) with Co(II), Ni(II) and Cu(II) chlorides, and Fe(III)and Zn(II)nitrat...

Metabolism of 4-chloro-2-nitrophenol in a gram-positive bacterium, Exiguobacterium sp. PMA.

Microb. Cell Fact. 11 , 150, (2012)

Chloronitrophenols (CNPs) are widely used in the synthesis of dyes, drugs and pesticides, and constitute a major group of environmental pollutants. 4-Chloro-2-nitrophenol (4C2NP) is an isomer of CNPs that has been detected in various industrial effluents. A n...

Characterization, molecular modeling and antimicrobial activity of metal complexes of tridentate Schiff base derived from 5-acetyl-4-hydroxy-2H-1,3-thiazine-2,6(3H)-dione and 2-aminophenol

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 95 , 483-90, (2012)

Graphical abstract

A synthetic model of the putative Fe(II)-iminobenzosemiquinonate intermediate in the catalytic cycle of o-aminophenol dioxygenases.

J. Am. Chem. Soc. 134(12) , 5460-3, (2012)

The oxidative ring cleavage of aromatic substrates by nonheme Fe dioxygenases is thought to involve formation of a ferrous-(substrate radical) intermediate. Here we describe the synthesis of the trigonal-bipyramdial complex Fe((Ph2)Tp)(ISQ(tBu)) (2), the firs...

Electrochemical copolymerization study of o-toluidine and o-aminophenol by the simultaneous EQCM and in situ FTIR spectroelectrochemistry.

Talanta 81(1-2) , 664-72, (2010)

The electrochemical synthesis and characterization of a copolymer, poly(o-toluidine-co-o-aminophenol), were conducted using in situ piezoelectric FTIR spectroelectrochemistry. The monomer feed ratio strongly affects the copolymerization rate and the propertie...