白屈氨酸

白屈氨酸结构式
白屈氨酸结构式
品牌特惠专场
常用名 白屈氨酸 英文名 chelidamic acid
CAS号 138-60-3 分子量 183.118
密度 1.7±0.1 g/cm3 沸点 428.3±45.0 °C at 760 mmHg
分子式 C7H5NO5 熔点 267 °C (dec.)(lit.)
MSDS 中文版 美版 闪点 212.8±28.7 °C
符号 GHS07
GHS07
信号词 Warning

Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase.

Biochem. Pharmacol. 34 , 4145-4150, (1985)

Twenty conformationally restricted analogues of glutamate including benzoic acids, hydroxy-benzoic acids, pyridine dicarboxylic acids, and pyran dicarboxylic acids were tested as inhibitors of glutamate decarboxylase from rat brain. Chelidonic acid, 2,6-pyrid...

Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives.

Anticancer Drug Des. 13(8) , 837-55, (1998)

We have explored the potential antitumour activity of DNA-intercalating free radical generators based on compounds constructed from 9-anilinoacridine and chelidamic acid as an iron (II) binding centre. Here we describe their synthesis, DNA cleaving ability an...

[Use of the radial hemolysis reaction for titrating antirabies sera].

Vopr. Virusol. 29(3) , 360-1, (1984)

[Antiviral activity of chelidamic acid derivatives].

Vopr. Virusol. 29(3) , 361-3, (1984)

Importance of hydrogen-bonding sites in the chiral recognition mechanism between racemic D3 terbium(III) complexes and amino acids.

Chirality 21(5) , 497-506, (2009)

The perturbation of the racemic equilibrium of luminescent D3 terbium(III) complexes with chelidamic acid (CDA), a hydroxylated derivative of 2,6-pyridine-dicarboxylic acid (DPA), by added chiral biomolecules such as L-amino acids has been studied using circu...

Complexation of copper(II)-Chelidamate: A multifrequency-pulsed electron paramagnetic resonance and electron nuclear double resonance analysis.

J. Phys. Chem. B 110(41) , 20655-63, (2006)

Multifrequency electron paramagnetic resonance (EPR) and electron nuclear double resonance (ENDOR) techniques were used to obtain structural information about the copper(II)-chelidamate complex. Well-resolved nitrogen ENDOR spectra could be recorded from soli...

Pseudopolymorphs of chelidamic acid and its dimethyl ester.

Acta Crystallogr. C 68(Pt 9) , o344-50, (2012)

Different tautomeric and zwitterionic forms of chelidamic acid (4-hydroxypyridine-2,6-dicarboxylic acid) are present in the crystal structures of chelidamic acid methanol monosolvate, C(7)H(5)NO(5)·CH(4)O, (Ia), dimethylammonium chelidamate (dimethylammonium ...

Tuning the keto equilibrium in 4-substituted dipicolinic acid derivatives.

Org. Biomol. Chem. 1(4) , 737-40, (2003)

The synthesis of 4-substituted dipicolinic acid derivatives requiring palladium catalysis is described. A keto-enol equilibrium has been observed, depending on the nature of the 2,6-position substituents.