喹乙醇； 喹酰胺醇结构式
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常用名 | 喹乙醇； 喹酰胺醇 | 英文名 | Olaquindox |
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| CAS号 | 23696-28-8 | 分子量 | 263.249 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 343.3ºC | |
| 分子式 | C12H13N3O4 | 熔点 | 209°C (dec.) | |
| MSDS | 中文版 美版 | 闪点 | >204.4ºC | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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First detection of oqxAB in Salmonella spp. isolated from food.
Antimicrob. Agents Chemother. 57(1) , 658-60, (2013) Food-borne salmonellosis is an important public health problem worldwide and the second leading cause of food-borne illnesses in Hong Kong. In this study, the prevalence and antimicrobial resistance of Salmonella in meat products in Hong Kong were determined.... |
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Reduction of carbadox mediated by reaction of Mn(III) with oxalic acid.
Environ. Sci. Technol. 47(3) , 1357-64, (2013) Manganese(III) geocomponents are commonly found in the soil environment, yet their roles in many biogeochemical processes remain unknown. In this study, we demonstrated that Mn(III) generated from the reaction of MnO(2) and oxalic acid caused rapid and extens... |
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Residue depletion and tissue-plasma correlation of methyl-3-quinoxaline-2-carboxylic acid after dietary administration of olaquindox in pigs.
J. Agric. Food Chem. 58(2) , 937-42, (2010) A residue depletion study was performed to investigate the tissue kinetics and tissue-plasma correlation of methyl-3-quinoxaline-2-carboxylic acid (MQCA), the marker residue of olaquindox (OLA), in pigs. Twenty-five pigs were randomly divided into a test and ... |
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Development of a biomimetic enzyme-linked immunosorbent assay method based on a hydrophilic molecularly imprinted polymer film for determination of olaquindox in chick feed samples.
J. Immunoassay Immunochem. 34(1) , 16-29, (2013) In this study, a new way to substitute the biology antibody was introduced by using a hydrophilic molecularly imprinted film, which was directly prepared on the well surface of MaxiSorp polystyrene 96-well plate by the bulk polymerization technique. This impr... |
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Metabolism of olaquindox in rat and identification of metabolites in urine and feces using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.
Rapid Commun. Mass Spectrom. 25(7) , 889-98, (2011) Olaquindox (OLA), N-(2-hydroxyethyl)-3-methyl-2-quinoxalincarboxamide-1,4-dioxide, is an antimicrobial and growth-promoting agent for animals, which has been banned or allowed only limited use for its potential toxicity. To thoroughly understand the metabolic... |
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Determination of Carbadox and metabolites of Carbadox and Olaquindox in muscle tissue using high performance liquid chromatography-tandem mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 881-882 , 90-5, (2012) A sensitive and robust LC-APCI-MS/MS method has been developed for the unambiguous detection and quantitative determination of the antimicrobial agent Carbadox, its metabolite quinoxaline-2-carboxylic acid and methyl-3-quinoxaline-2-carboxylic acid the major ... |
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Two generation reproduction and teratogenicity studies of feeding cyadox in Wistar rats.
Food Chem. Toxicol. 49(5) , 1068-79, (2011) To investigate the teratogenic potential and reproductive toxicity of cyadox, a growth promoting agent, Wistar rats (F(0)) were fed with diets containing cyadox (0, 50, 150 and 2500 mg/kg) or olaquindox (150 mg/kg), approximately equivalent to cyadox 5, 15, 2... |
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Development of an on-line molecularly imprinted chemiluminescence sensor for determination of trace olaquindox in chick feeds.
J. Sci. Food Agric. 92(13) , 2696-702, (2012) Olaquindox, as one of the antimicrobial growth accelerants, is usually used in livestock production to improve feed efficiency. Due to health concerns over possible carcinogenic, mutagenic and photoallergenic effects of olaquindox on animals, the development ... |
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The metabolism of olaquindox in rats, chickens and pigs.
Toxicol. Lett. 200(1-2) , 24-33, (2011) Olaquindox is a growth-promoting feed additive for food-producing animals. Its toxicities were reported to be closely related to the metabolism. To provide the interpretation of toxicities in animals, this study explored the metabolism of olaquindox in rats, ... |
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Pharmacokinetic and residue studies of quinolone compounds and olaquindox in poultry.
Ann. Rech. Vet. 21 Suppl 1 , 137S-144S, (1990) Nalidixic acid and similar antimicrobial agents have been available for more than 20 years, mainly for treating infections caused by Gram-negative enterobacteria. Recently, several chemically related drugs, including oxolinic acid, pipemidic acid, piromidic a... |