L-2-氨基丁酸

Clin. Chim. Acta 361(1-2) , 150-8, (2005)

Previous work by others have suggested the occurrence of one or more chemical or metabolic 'markers' for ME/CFS including specific amino acids and organic acids and a number of unidentified compounds (CFSUM1, CFSUM2). We have shown elsewhere that CFSUM1 is pa...

J. Clin. Gastroenterol. 33(1) , 36-40, (2001)

D-Xylose absorption testing is a simple, low-cost method of screening for small intestinal malabsorption. The optimum method to measure D-xylose absorption (serum vs. urine testing) is uncertain.We present a method of improving the accuracy of D-xylose testin...

Anal. Chem. 83(7) , 2705-11, (2011)

Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few internal standards representing all metabolites, the ultimate re...

Clin. Chem. Lab Med. 42(2) , 186-91, (2004)

24S-Hydroxycholesterol (24OHC) and 27-hydroxycholesterol (27OHC) are two structurally similar oxysterols of different origins--the former almost exclusively formed in the brain and the latter formed to a lesser extent in the brain than in most other organs. H...

Blood Purif. 18(2) , 97-102, (2000)

The purpose of this study was to examine the effect of nocturnal hemodialysis (NHD) on serum amino acid (AA) profile.In a cross-over trial, we studied the AA profile in 11 patients who were switched from conventional hemodialysis to NHD. Plasma levels of AA w...

Nephrol. Dial. Transplant. 17(6) , 1032-6, (2002)

Pteridine metabolism is impaired in the uraemic state. This may affect cardiovascular function and contribute to malnutrition. We wished to clarify further the impact of impaired pteridine metabolism.Using the HPLC method, the plasma concentrations of endogen...

J. Chromatogr. A. 272(2) , 279-85, (1983)

The levels of putrescine, cadaverine, spermidine and spermine in uremic plasma were determined with an automatic polyamine analyzer with a 7.5 X 0.2 cm I.D. cation-exchange column using a stepwise sodium chloride gradient. All four polyamines were higher in t...

Br. J. Anaesth. 86(4) , 578-80, (2001)

Nitric oxide synthase requires tetrahydrobiopterin for its activity. In animal models of sepsis, changes in circulating tetrahydrobiopterin concentrations precede increases in nitrate. We measured plasma tetrahydrobiopterin and nitrate concentrations on three...

Clin. Chim. Acta 336(1-2) , 1-12, (2003)

NO synthesis is inhibited by the dimethylarginine (DMA) ADMA, which accumulates, similar to SDMA, in the plasma of patients suffering from chronic renal failure (CRF). ADMA and possibly SDMA contribute to hypertension and atherosclerosis in patients with chro...

Clin. J. Am. Soc. Nephrol. 1(2) , 281-7, (2006)

Myeloperoxidase (MPO), which is secreted during activation of neutrophils, may serve as one mechanistic link among persistent inflammation, oxidative stress, and cardiovascular disease. This study related MPO activity to inflammatory and oxidative stress biom...