盐酸雷尼替丁
盐酸雷尼替丁结构式
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常用名 | 盐酸雷尼替丁 | 英文名 | Ranitidine hydrochloride |
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| CAS号 | 66357-59-3 | 分子量 | 350.865 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C13H23ClN4O3S | 熔点 | 134°C (dec.) | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Histamine inhibits differentiation of skin fibroblasts into myofibroblasts.
Biochem. Biophys. Res. Commun. 463 , 434-9, (2015) Histamine and TGF-β, major mediators secreted by mast cells, are involved in skin inflammation and play critical roles in the pathogenesis of systemic sclerosis. However, the roles of signaling mechanisms in the development of skin fibrosis remain largely unc... |
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Involvement of histaminergic inputs in the jaw-closing reflex arc.
J. Neurophysiol. 113 , 3720-35, (2015) Histamine receptors are densely expressed in the mesencephalic trigeminal nucleus (MesV) and trigeminal motor nucleus. However, little is known about the functional roles of neuronal histamine in controlling oral-motor activity. Thus, using the whole-cell rec... |
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Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants.
Ecotoxicol. Environ. Saf. 108 , 52-7, (2014) Pharmaceutically active compounds (PACs) are continuously dispersed into the environment due to human and veterinary use, giving rise to their potential accumulation in edible plants. In this study, Eruca sativa L. and Zea mays L. were selected to determine t... |
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Morphine glucuronidation increases its analgesic effect in guinea pigs.
Life Sci. 109(2) , 104-10, (2014) Morphine is extensively metabolized to neurotoxic morphine-3-glucuronide (M3G) and opioid agonist morphine-6-glucuronide (M6G). Due to these different roles, interindividual variability and co-administration of drugs that interfere with metabolism may affect ... |
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Cerebellar vermis H₂ receptors mediate fear memory consolidation in mice.
Neurosci. Lett. 587 , 57-61, (2015) Histaminergic fibers are present in the molecular and granular layers of the cerebellum and have a high density in the vermis and flocullus. Evidence supports that the cerebellar histaminergic system is involved in memory consolidation. Our recent study showe... |
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[The development of hemorrhagic vasculitis (Schönlein-Henoch disease) in a patient with a chronic stomach ulcer against a background of Sostril (ranitidine hydrochloride) therapy].
Vestn. Khir. Im. I. I. Grek. 152(1-2) , 102-3, (1994)
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Clinical challenge. Esophageal hiatal hernia.
J. Zoo Wildl. Med. 45(4) , 999-1001, (2014)
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Ranitidine hydrochloride.
Drug Intell. Clin. Pharm. 17(12) , 873-85, (1983) Ranitidine is a selective, competitive histamine H2-receptor antagonist recently approved by the Food and Drug Administration for use in the short-term treatment of active duodenal ulcers and gastric hypersecretory conditions. Ranitidine is four to ten times ... |
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Chromatographic methods for determining the identity, strength and purity of ranitidine hydrochloride both in the drug substance and its dosage from—an exercise in method selection, development, definition and validation
J. Pharm. Biomed. Anal. 7(1) , 1-22, (1989) The selection, development, definition and validation of selective stability-indicating procedures for high-performance liquid chromatographic and thin-layer chromatographic analyses of ranitidine hydrochloride are described. The procedures used in conjunctio... |
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Signal transduction mechanism of biased ligands at histamine H2 receptors.
Biochem. J. 459(1) , 117-26, (2014) 7TMRs (seven-transmembrane receptors) exist as conformational collections in which different conformations would lead to differential downstream behaviours such as receptor phosphorylation, G-protein activation and receptor internalization. In this context, a... |