菲尼酮结构式
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常用名 | 菲尼酮 | 英文名 | Phenidone |
|---|---|---|---|---|
| CAS号 | 92-43-3 | 分子量 | 162.189 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 304.1±25.0 °C at 760 mmHg | |
| 分子式 | C9H10N2O | 熔点 | 119-121 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 137.7±23.2 °C | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
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Antioxidant and Anti-inflammatory Activities of Essential Oil and Extracts of Piper miniatum.
Nat. Prod. Commun. 10 , 2005-8, (2016) The chemical composition of the essential oil and antioxidant and anti-inflammatory activities of the extracts from Piper miniatum were determined. GC and GC-MS analysis of the essential oil resulted in the identification of 64 components, accounting for 89.2... |
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Phenidone attenuates oxygen/glucose deprivation-induced neurotoxicity by antioxidant and antiapoptotic action in mouse cortical cultures.
Neurosci. Lett. 272(2) , 91-4, (1999) The abrupt elevation in the levels of cyclooxygenase or lipoxygenase metabolites of arachidonic acid during cerebral ischemia contributes to neuronal injury. Recently, evidence has accumulated that both excitotoxic and apoptotic features can coexist in ischem... |
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The role of jasmonates in floral nectar secretion.
PLoS ONE 5(2) , e9265, (2010) Plants produce nectar in their flowers as a reward for their pollinators and most of our crops depend on insect pollination, but little is known on the physiological control of nectar secretion. Jasmonates are well-known for their effects on senescence, the d... |
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Phenidone prevents kainate-induced neurotoxicity via antioxidant mechanisms.
Brain Res. 874(1) , 15-23, (2000) Acculmulating evidence indicates that a marked generation of oxygen free radicals derived from the metabolism of arachidonic acid causes neurodegeneration. Recently, we have demonstrated that the novel antioxidant actions mediated by phenidone, a dual inhibit... |
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Endothelin-1 stimulates aldosterone synthesis in Conn's adenomas via both A and B receptors coupled with the protein kinase C- and cyclooxygenase-dependent signaling pathways.
J. Investig. Med. 48(5) , 343-50, (2000) The mechanisms and factors leading to enhanced aldosterone secretion and ultimately to neoplastic transformation of the adrenal cortex are poorly defined. Angiotensin-II (Ang-II) and endothelin-1 (ET-1) have emerged as likely candidates among potential aldost... |
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Transcriptional activation of Igl, the gene for indole formation in Zea mays: a structure-activity study with elicitor-active N-acyl glutamines from insects.
Phytochemistry 65(8) , 1047-55, (2004) The indole-3-glycerol phosphate lyase Igl is the structural gene of volatile indole biosynthesis in the tritrophic interaction in maize. The gene is activated on transcriptional level with the same kinetics and to the same level by the fatty acid-amino acid c... |
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Eicosanoid biosynthesis inhibitors influence mortality of Pieris brassicae larvae co-injected with fungal conidia.
Arch. Insect Biochem. Physiol. 63(3) , 93-100, (2006) Influence of fungal species (conidia spores) on mortality of Pieris brassicae larvae differed when injected into the larvae. The effects of B. bassiana (ARSEF-1151) were expressed in a conidial dose-dependent manner on mortality of the larvae. An increased an... |
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Reducing jasmonic acid levels causes ein2 mutants to become ethylene responsive.
FEBS Lett. 587(2) , 226-30, (2013) It has previously been shown that jasmonic acid affects the ethylene signaling pathway. EIN2 is a central component of ethylene signaling that is downstream of the receptors. EIN2 has previously been shown to be required for ethylene responses. We found that ... |
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The influence of chronic eicosanoid biosynthesis inhibition on life history of the greater waxmoth, Galleria mellonella and its ectoparasitoid, Bracon hebetor.
J. Insect Physiol. 57(4) , 501-7, (2011) Eicosanoids are oxygenated metabolites of three C20 polyunsaturated fatty acids, mainly arachidonic acid (AA; 20:4n-6), but also 20:3n-6 and 20:5n-3. Aside from their importance in biomedicine, eicosanoids act in invertebrate biology. Prostaglandins (PGs) inf... |
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Is ATP a substrate for 15-lipoxygenase?
Biochem. Cell Biol. 78(2) , 87-91, (2000) Lipoxygenases catalyze peroxidation of polyunsaturated fatty acids containing the 1-cis, 4-cis pentadiene structure. Linoleic (18:2), linolenic (18:3), and arachidonic (20:4) acids are the predominant substrates for this class of enzymes. Effects of 15-lipoxy... |