氯霉素
氯霉素结构式
|
常用名 | 氯霉素 | 英文名 | Chloramphenicol |
|---|---|---|---|---|
| CAS号 | 56-75-7 | 分子量 | 323.129 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 563.2±60.0 °C at 760 mmHg | |
| 分子式 | C11H12Cl2N2O5 | 熔点 | 148-150 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 294.4±32.9 °C | |
| 符号 |
GHS08 |
信号词 | Danger |
|
Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.
PLoS Pathog. 11(2) , e1004645, (2015) The identification of Mycobacterium tuberculosis genes necessary for persistence in vivo provides insight into bacterial biology as well as host defense strategies. We show that disruption of M. tuberculosis membrane protein PerM (Rv0955) resulted in an IFN-γ... |
|
|
Improved production of propionic acid in Propionibacterium jensenii via combinational overexpression of glycerol dehydrogenase and malate dehydrogenase from Klebsiella pneumoniae.
Appl. Environ. Microbiol. 81(7) , 2256-64, (2015) Microbial production of propionic acid (PA), an important chemical building block used as a preservative and chemical intermediate, has gained increasing attention for its environmental friendliness over traditional petrochemical processes. In previous studie... |
|
|
A vaccine formulation combining rhoptry proteins NcROP40 and NcROP2 improves pup survival in a pregnant mouse model of neosporosis.
Vet. Parasitol. 207(3-4) , 203-15, (2015) Currently there are no effective vaccines for the control of bovine neosporosis. During the last years several subunit vaccines based on immunodominant antigens and other proteins involved in adhesion, invasion and intracellular proliferation of Neospora cani... |
|
|
Identification and characterization of fusolisin, the Fusobacterium nucleatum autotransporter serine protease.
PLoS ONE 9(10) , e111329, (2014) Fusobacterium nucleatum is an oral anaerobe associated with periodontal disease, adverse pregnancy outcomes and colorectal carcinoma. A serine endopeptidase of 61-65 kDa capable of damaging host tissue and of inactivating immune effectors was detected previou... |
|
|
The fused anthranilate synthase from Streptomyces venezuelae functions as a monomer.
Mol. Cell Biochem. 400(1-2) , 9-15, (2015) Recently, we showed that the fused chorismate-utilizing enzyme from the antibiotic-producing soil bacterium Streptomyces venezuelae is an anthranilate synthase (designated SvAS), not a 2-amino-2-deoxyisochorismate (ADIC) synthase, as was predicted based on it... |
|
|
Brucella abortus depends on pyruvate phosphate dikinase and malic enzyme but not on Fbp and GlpX fructose-1,6-bisphosphatases for full virulence in laboratory models.
J. Bacteriol. 196(16) , 3045-57, (2014) The brucellae are the etiological agents of brucellosis, a worldwide-distributed zoonosis. These bacteria are facultative intracellular parasites and thus are able to adjust their metabolism to the extra- and intracellular environments encountered during an i... |
|
|
Phenotypic heterogeneity enables uropathogenic Escherichia coli to evade killing by antibiotics and serum complement.
Infect. Immun. 83(3) , 1056-67, (2015) Uropathogenic strains of Escherichia coli (UPEC) are the major cause of bacteremic urinary tract infections. Survival in the bloodstream is associated with different mechanisms that help to resist serum complement-mediated killing. While the phenotypic hetero... |
|
|
Dual-species relations between Candida tropicalis isolated from apple juice ultrafiltration membranes, with Escherichia coli O157:H7 and Salmonella sp.
J. Appl. Microbiol. 118(2) , 431-42, (2015) The objective of this study was to determine the interactions between common spoilage yeast, Candida tropicalis, isolated from ultrafiltration membranes, and Escherichia coli O157:H7 and Salmonella sp. on stainless steel surfaces.Single and dual-species attac... |
|
|
A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis.
Nat. Commun. 6 , 7286, (2015) During angiogenesis, Rho-GTPases influence endothelial cell migration and cell-cell adhesion; however it is not known whether they control formation of vessel lumens, which are essential for blood flow. Here, using an organotypic system that recapitulates dis... |
|
|
BoHV-4 immediate early 1 gene is a dispensable gene and its product is not a bone marrow stromal cell antigen 2 counteracting factor.
BMC Vet. Res. 11 , 224, (2015) Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus whose genome was cloned as Bacterial Artificial Chromosome (BAC) and exploited as a gene delivery vector for vaccine purposes. Although BoHV-4 genome has been completely sequenced and its open reading frames... |