L-组氨酸
L-组氨酸结构式
|
常用名 | L-组氨酸 | 英文名 | L-Histidine |
|---|---|---|---|---|
| CAS号 | 71-00-1 | 分子量 | 155.155 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 458.9±35.0 °C at 760 mmHg | |
| 分子式 | C6H9N3O2 | 熔点 | 282 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 231.3±25.9 °C |
|
Salicylic acid signaling controls the maturation and localization of the arabidopsis defense protein ACCELERATED CELL DEATH6.
Mol. Plant 7(8) , 1365-83, (2014) ACCELERATED CELL DEATH6 (ACD6) is a multipass membrane protein with an ankyrin domain that acts in a positive feedback loop with the defense signal salicylic acid (SA). This study implemented biochemical approaches to infer changes in ACD6 complexes and local... |
|
|
G-quadruplex conformation and dynamics are determined by loop length and sequence.
Nucleic Acids Res. 42(12) , 8106-14, (2014) The quadruplex forming G-rich sequences are unevenly distributed throughout the human genome. Their enrichment in oncogenic promoters and telomeres has generated interest in targeting G-quadruplex (GQ) for an anticancer therapy. Here, we present a quantitativ... |
|
|
Der p 11 is a major allergen for house dust mite-allergic patients suffering from atopic dermatitis.
J. Invest. Dermatol. 135(1) , 102-9, (2014) House dust mites (HDMs) belong to the most potent indoor allergen sources worldwide and are associated with allergic manifestations in the respiratory tract and the skin. Here we studied the importance of the high-molecular-weight group 11 allergen from Derma... |
|
|
Autoantibodies specific to D4GDI modulate Rho GTPase mediated cytoskeleton remodeling and induce autophagy in T lymphocytes.
J. Autoimmun. 58 , 78-89, (2015) T lymphocytes from patients with Systemic Lupus Erythematosus (SLE) display multiple abnormalities, including increased cell activation, abnormal cell death by apoptosis and impairment of autophagy pathway. In the present study we report the presence of speci... |
|
|
Ultrasonication as a potential tool to predict solute crystallization in freeze-concentrates.
Pharm. Res. 31(6) , 1512-24, (2014) We hypothesize that ultrasonication can accelerate solute crystallization in freeze-concentrates. Our objective is to demonstrate ultrasonication as a potential predictive tool for evaluating physical stability of excipients in frozen solutions.The crystalliz... |
|
|
The CRE1 cytokinin pathway is differentially recruited depending on Medicago truncatula root environments and negatively regulates resistance to a pathogen.
PLoS ONE 10(1) , e0116819, (2015) Cytokinins are phytohormones that regulate many developmental and environmental responses. The Medicago truncatula cytokinin receptor MtCRE1 (Cytokinin Response 1) is required for the nitrogen-fixing symbiosis with rhizobia. As several cytokinin signaling gen... |
|
|
Rheological characterization and injection forces of concentrated protein formulations: an alternative predictive model for non-Newtonian solutions.
Eur. J. Pharm. Biopharm. 87(2) , 318-28, (2014) Development of injection devices for subcutaneous drug administration requires a detailed understanding of user capability and forces occurring during the drug administration process. Injection forces of concentrated protein therapeutics are influenced by syr... |
|
|
Dose levels in particulate-containing formulations impact anti-drug antibody responses to murine monoclonal antibody in mice.
J. Pharm. Sci. 104(5) , 1610-21, (2015) Dosage levels and particulate contents of therapeutic protein formulations are potential factors that impact immunogenicity of protein therapeutics. Here, we evaluated the effect of dose levels on the immunogenicity of protein particulates formed by adsorbing... |
|
|
Dissection of key determinants of cleavage activity in signal peptidase III (SPaseIII) PibD.
Extremophiles 18(5) , 905-13, (2014) In Archaea, type IV prepilins and prearchaellins are processed by designated signal peptidase III (SPaseIII) prior to their incorporation into pili and the archaellum, respectively. These peptidases belong to the family of integral membrane aspartic acid prot... |
|
|
Tyrosine phosphorylation of HSC70 and its interaction with RFC mediates methotrexate resistance in murine L1210 leukemia cells.
Cancer Lett. 357(1) , 231-41, (2014) We previously identified and characterized a 66-68 kDa membrane-associated, tyrosine phosphorylated protein in murine leukemia L1210 cells as HSC70 which is a methotrexate (MTX)-binding protein. In order to further characterize the functional role of HSC70 in... |