4,4'-四甲基二氨基二苯甲烷结构式
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常用名 | 4,4'-四甲基二氨基二苯甲烷 | 英文名 | 4,4'-Methylenebis(N,N-dimethylaniline) |
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| CAS号 | 101-61-1 | 分子量 | 254.37000 | |
| 密度 | N/A | 沸点 | 390 °C | |
| 分子式 | C17H22N2 | 熔点 | 88-89 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 178 °C | |
| 符号 |
GHS08, GHS09 |
信号词 | Danger |
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Disposition and metabolism of the carcinogen reduced Michler's ketone in rats.
Cancer Res. 42(9) , 3475-9, (1982) Studies on the in vivo and in vitro disposition of 4,4'-[14C]-methylenebis(N,N-dimethyl)benzamine (reduced Michler's ketone, RMK) were performed. Osborne-Mendel rats retained, after 24 hr, 78% of a p.o. dose of [14C]RMK. At 24 hr after an i.p. dose, fat, live... |
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4,4'-Methylenebis(N,N-dimethyl)benzenamine.
IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 27 , 119-26, (1982)
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[Antiarrhythmic effects of bis(dimethyl amino)-diphenyl methane (BDDM)].
Yao Xue Xue Bao 23(6) , 448-51, (1988)
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4,4'-Methylenebis(N,N-dimethyl)benzenamine.
Rep. Carcinog. 12 , 264-5, (2011)
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4,4'-Methylenebis(N,N-dimethyl)benzenamine.
Rep. Carcinog. 11 , III168, (2004)
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[A convenient method of isoflavonone synthesis].
Bioorg. Khim. 32(4) , 444-5, (2006) Reaction of 2-hydroxydeoxybenzoins with bis(dimethylamino)methane in ethanol results in isoflavonones. |
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4,4'-Methylenebis(N,N-dimethyl)benzenamine.
Rep. Carcinog. 10 , 151, (2002)
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[Tetramethyldiaminodiphenylmethane--a universal reagent for drug detection].
Soud. Lek. 37(4) , 62-3, (1992) Many a drug was identified by thin layer chromatography when using tetramethyldiaminodiphenylmethan (TDM) as a universal reagent subsequently to chlorination. This non-carcinogenic compound yields a characteristical tint with all the drugs and their metabolit... |
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Promotive effect of 4,4'-methylenebis(N,N-dimethyl)benzenamine on N-bis(2-hydroxypropyl)nitrosamine-induced thyroid tumors in Wistar rats.
Cancer Lett. 40(3) , 275-81, (1988) The promotive effect of 4,4'-methylenebis(N,N-dimethyl)benzenamine (MDBA) on 2-stage thyroid tumorigenesis induced by N-bis(2-hydroxypropyl)nitrosamine (DHPN) in Wistar male rats was investigated. Animals were given i.p. injections of DHPN, and then a basal d... |
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Mutagenicity studies with o-tolidine and 4,4'-tetramethyldiaminodiphenylmethane.
Mutat. Res. 89(3) , 197-202, (1981) This paper confirms the mutagenicity of 2 carcinogenic chemicals, o-tolidine and 4,4'-tetramethyldiaminodiphenylmethane (TDDM). o-Tolidine and TDDM were both tested in the Salmonella/mammalian-microsome test and in the sister-chromatid exchange (SCE) test wit... |