硫化砷(III)

Drug Des. Devel. Ther. 9 , 79-92, (2015)

Arsenic sulfide (As4S4), the main component of realgar, a traditional Chinese medicine, has shown antitumor efficacy in several tumor types, especially for acute promyelocytic leukemia. In this study, we aimed to explore the efficacy and mechanism of As4S4 in...

Proc. Natl. Acad. Sci. U. S. A. 107(50) , 21683-8, (2010)

Arsenic, a curative agent for acute promyelocytic leukemia, induces cell apoptosis and degradation of BCR-ABL in chronic myelogenous leukemia (CML). We demonstrated that ubiquitination and degradation of BCR-ABL was mediated by c-CBL, a RING-type E3 ligase th...

Proc. Natl. Acad. Sci. U. S. A. 106(9) , 3378-83, (2009)

In this study, we show that combined use of Imatinib (IM) and arsenic sulfide [As(4)S(4) (AS)] exerts more profound therapeutic effects in a BCR/ABL-positive mouse model of chronic myeloid leukemia (CML) than either drug as a single agent. A systematic analys...

Rapid Commun. Mass Spectrom. 24(1) , 95-102, (2010)

Ternary chalcogenide As-S-Se glasses, important for optics, computers, material science and technological applications, are often made by pulsed laser deposition (PLD) technology but the plasma composition formed during the process is mostly unknown. Therefor...

Opt. Express 18(25) , 26666-74, (2010)

We computationally investigate supercontinuum generation in an As(2)S(3) solid core photonic crystal fiber (PCF) with a hexagonal cladding of air holes. We study the effect of varying the system (fiber and input pulse) parameters on the output bandwidth. We f...

Appl. Environ. Microbiol. 75(21) , 6896-9, (2009)

Shewanella sp. strain HN-41 was previously shown to produce novel, photoactive, As-S nanotubes via the reduction of As(V) and S(2)O(3)(2-) under anaerobic conditions. To determine if this ability was unique to this bacterium, 10 different Shewanella strains, ...

J. Emerg. Med. 44(2) , 367-72, (2013)

Because the toxicity of arsenic is well known, arsenic-containing compounds have frequently been ingested for suicidal purposes. We report a case of attempted suicide by massive ingestion of arsenic trisulfide, an arsenic mineral of low solubility, which resu...

Environ. Int. 37(5) , 889-92, (2011)

Toasting friends and family with realgar wines and painting children's foreheads and limbs with the leftover realgar/alcohol slurries is an important customary ritual during the Dragon Boat Festival (DBF); a Chinese national holiday and ancient feast day cele...

Appl. Opt. 50(14) , 1974-8, (2011)

We demonstrate micrometer scale mid-IR lenses for integrated optics, using solution-based inkjet printing techniques and subsequent processing. Arsenic sulfide spherical microlenses with diameters of 10-350 μm and focal lengths of 10-700 μm have been fabricat...

Environ. Microbiol. 15(10) , 2748-60, (2013)

Strain MPA-C3 was isolated by incubating arsenic-bearing sediments under anaerobic, mesophilic conditions in minimal media with acetate as the sole source of energy and carbon, and As(V) as the sole electron acceptor. Following growth and the respiratory redu...