睾酮
睾酮结构式
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常用名 | 睾酮 | 英文名 | Testosterone |
|---|---|---|---|---|
| CAS号 | 58-22-0 | 分子量 | 288.424 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 432.9±45.0 °C at 760 mmHg | |
| 分子式 | C19H28O2 | 熔点 | 152-156 °C | |
| MSDS | 中文版 美版 | 闪点 | 184.7±21.3 °C | |
| 符号 |
GHS02, GHS07 |
信号词 | Danger |
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Osteopontin deletion prevents the development of obesity and hepatic steatosis via impaired adipose tissue matrix remodeling and reduced inflammation and fibrosis in adipose tissue and liver in mice.
PLoS ONE 9(5) , e98398, (2014) Osteopontin (OPN) is a multifunctional extracellular matrix (ECM) protein involved in multiple physiological processes. OPN expression is dramatically increased in visceral adipose tissue in obesity and the lack of OPN protects against the development of insu... |
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Potential effects of aerobic exercise on the expression of perilipin 3 in the adipose tissue of women with polycystic ovary syndrome: a pilot study.
Eur. J. Endocrinol. 172(1) , 47-58, (2014) Polycystic ovary syndrome (PCOS) is associated with reduced adipose tissue lipolysis that can be rescued by aerobic exercise. We aimed to identify differences in the gene expression of perilipins and associated targets in adipose tissue in women with PCOS bef... |
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Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry.
J. Steroid Biochem. Mol. Biol. 152 , 142-54, (2015) Androsta-1,4,6-triene-3,17-dione (ATD) is an irreversible steroidal aromatase inhibitor and is marketed as a supplement. It has been reported to effectively reduce estrogen biosynthesis and significantly increase the levels of endogenous steroids such as dihy... |
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Enhanced Suppression of Fertility Can be Achieved by Priming with FSHR and Eppin and Further Boosting with Their B-cell Epitope Peptides.
Am. J. Reprod. Immunol. 74 , 156-68, (2015) In our previous study on adult male mice, we had identified one immunodominant epitope in hEppin and three epitopes in hFSHR that caused fertility inhibition. But it only demonstrated a moderate inhibitory effect on fertility, and the antifertility effect was... |
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Characterization of a highly sensitive and selective novel trapping reagent, stable isotope labeled glutathione ethyl ester, for the detection of reactive metabolites.
J. Pharmacol. Toxicol. Methods 76 , 83-95, (2015) Glutathione (GSH) trapping assays are widely used to predict the post-marketing risk for idiosyncratic drug reactions (IDRs) in the pharmaceutical industry. Although several GSH derivatives have been introduced as trapping reagents for reactive intermediates,... |
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KISS1 can be used as a novel target for developing a DNA immunocastration vaccine in ram lambs.
Vaccine 33(6) , 777-82, (2015) KISS1 gene-encoding kisspeptins are critical for the onset of puberty and control of adult fertility. This study investigated whether KISS1 can be used as a novel target for immunocastration. Human KISS1 was fused with the HBsAg-S gene for constructing an ant... |
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Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome.
PLoS ONE 10 , e0127595, (2015) To evaluate multiple follicular development synchronization after estrogen stimulation in prepubertal mice, follicular responsiveness to gonadotropin superovulation, the prospective reproductive potential and ovarian polycystic ovary syndrome (PCOS)-like symp... |
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Influence of resistance exercise intensity and metabolic stress on anabolic signaling and expression of myogenic genes in skeletal muscle.
Muscle Nerve 51(3) , 434-42, (2015) We investigated the effect of resistance exercise intensity and exercise-induced metabolic stress on the activation of anabolic signaling and expression of myogenic genes in skeletal muscle.Ten strength-trained athletes performed high-intensity [HI, 74% of 1-... |
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Mitochondrial proteomic analysis reveals the molecular mechanisms underlying reproductive toxicity of zearalenone in MLTC-1 cells.
Toxicology 324 , 55-67, (2014) Zearalenone (ZEA), a Fusarium mycotoxin that contaminates cereal crops worldwide, has been shown to affect the male reproductive system and trigger reactive oxygen species (ROS) generation. However, the mechanisms of its toxicity have not been fully understoo... |
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Ablation of androgen receptor gene triggers right ventricular outflow tract ventricular tachycardia.
Int. J. Cardiol. 189 , 172-81, (2015) Sex hormones and calcium (Ca(2+)) regulation play roles in the pathophysiology of ventricular tachycardia from right ventricular outflow tract (RVOT). The purpose of this study was to evaluate whether androgen receptor knockout (ARKO) can increase RVOT arrhyt... |