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3-[6-[[4-(三氟甲氧基)苯基]氨基]-4-嘧啶基]苯甲酰胺

3-[6-[[4-(三氟甲氧基)苯基]氨基]-4-嘧啶基]苯甲酰胺结构式
3-[6-[[4-(三氟甲氧基)苯基]氨基]-4-嘧啶基]苯甲酰胺结构式
品牌特惠专场
常用名 3-[6-[[4-(三氟甲氧基)苯基]氨基]-4-嘧啶基]苯甲酰胺 英文名 GNF-2
CAS号 778270-11-4 分子量 374.317
密度 1.4±0.1 g/cm3 沸点 536.4±50.0 °C at 760 mmHg
分子式 C18H13F3N4O2 熔点 N/A
MSDS 中文版 美版 闪点 278.2±30.1 °C
符号 GHS07
GHS07
信号词 Warning

Allosteric inhibitors of Bcr-abl-dependent cell proliferation.

Nat. Chem. Biol. 2 , 95-102, (2006)

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder characterized at the molecular level by the expression of Bcr-abl, a 210-kDa fusion protein with deregulated tyrosine kinase activity. Encouraged by the clinical validation of Bcr-abl as the ...

Inhibitors of Bcr-abl... breaking new ground again.

Nat. Chem. Biol. 2nd ed.,, 63-64, (2006)