9-芴醇
9-芴醇结构式
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常用名 | 9-芴醇 | 英文名 | 9-fluorenol |
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| CAS号 | 1689-64-1 | 分子量 | 182.218 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 367.5±11.0 °C at 760 mmHg | |
| 分子式 | C13H10O | 熔点 | 153-154 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 131.3±11.5 °C |
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Rational design of indoleamine 2,3-dioxygenase inhibitors.
J. Med. Chem. 53 , 1172-89, (2010) Indoleamine 2,3-dioxygenase (IDO) is an important therapeutic target for the treatment of diseases such as cancer that involve pathological immune escape. We have used the evolutionary docking algorithm EADock to design new inhibitors of this enzyme. First, w... |
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A gold nanoparticle-based colorimetric probe for rapid detection of 1-hydroxypyrene in urine.
Analyst 140 , 4662-7, (2015) Direct and rapid detection of 1-hydroxypyrene (1-OHP) is of great importance owing to its high carcinogenicity, teratogenicity and toxicity. In this study, a simple colorimetric assay for rapid determination of 1-OHP is reported, which is based on non-crossli... |
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Assessing hazardous risks of indoor airborne polycyclic aromatic hydrocarbons in the kitchen and its association with lung functions and urinary PAH metabolites in kitchen workers.
Clin. Chim. Acta 452 , 204-13, (2015) Indoor air pollution is associated with decreased pulmonary function but the relative impact of pollution from kitchen sources on health risks in kitchen workers is not well-known or studied. A study was conducted to measure the kitchen indoor air quality inc... |
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A transcriptional luxAB reporter fusion responding to fluorene in Sphingomonas sp. LB126 and its initial characterisation for whole-cell bioreporter purposes.
Res. Microbiol. 152(10) , 849-59, (2001) The promoter probe mini-Tn5-luxAB-tet was used to create a luxAB transcriptional fusion responding to fluorene in the fluorene utilising bacterium Sphingomonas sp. LB126. The mutant strain, named L-132, was impaired in fluorene utilisation and strongly emitte... |
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Metabolism of alcohol and ketone by cytochrome P-450 oxygenase: fluoren-9-ol in equilibrium with fluoren-9-one.
Drug Metab. Dispos. 12(4) , 421-6, (1984) Fluoren-9-ol and fluoren-9-one were used as model substrates to study microsomal metabolism of alcohols and carbonyl compounds. It was found that there was an oxidoreductase(s) present in the microsomal preparation that catalyzed interconversion of this alcoh... |
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Wake promoting agents: Search for next generation modafinil, lessons learned: Part III
Bioorg. Med. Chem. Lett. 22(11) , 3751-3, (2012) In searching for a next generation molecule to the novel wake promoting agent modafinil (compound 1), a series of fluorene-derived wakefulness enhancing agents were developed and evaluated in rat. Extensive pharmacokinetic studies of a potent member (compound... |
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Microbial reduction of 9-fluorenone to 9-hydroxyfluorene in carbon-filtered water: a confounding factor in an aquatic bioassay of 9-fluorenone with larvae of the midge, Chironomus tentans (Fabr.).
Bull. Environ. Contam. Toxicol. 75(6) , 1060-6, (2005)
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