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镁-吲哚-1乙酰氧甲酯

镁-吲哚-1乙酰氧甲酯结构式
镁-吲哚-1乙酰氧甲酯结构式
品牌特惠专场
常用名 镁-吲哚-1乙酰氧甲酯 英文名 Mag-indo-1/AM
CAS号 130926-94-2 分子量 612.58100
密度 1.335g/cm3 沸点 789.9ºC at 760mmHg
分子式 C30H32N2O12 熔点 N/A
MSDS 中文版 美版 闪点 431.5ºC

Quantitative TCR:pMHC Dissociation Rate Assessment by NTAmers Reveals Antimelanoma T Cell Repertoires Enriched for High Functional Competence.

J. Immunol. 195 , 356-66, (2015)

Experimental models demonstrated that therapeutic induction of CD8 T cell responses may offer protection against tumors or infectious diseases providing that T cells have sufficiently high TCR/CD8:pMHC avidity for efficient Ag recognition and consequently str...

Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR-Ligand Off-Rates Measurements on Living Cells.

Cancer Res. 75 , 1983-91, (2015)

The avidity of the T-cell receptor (TCR) for antigenic peptides presented by the peptide-MHC (pMHC) on cells is a key parameter for cell-mediated immunity. Yet a fundamental feature of most tumor antigen-specific CD8(+) T cells is that this avidity is low. In...