Mag-indo-1/AM
Mag-indo-1/AM structure
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Common Name | Mag-indo-1/AM | ||
|---|---|---|---|---|
| CAS Number | 130926-94-2 | Molecular Weight | 612.58100 | |
| Density | 1.335g/cm3 | Boiling Point | 789.9ºC at 760mmHg | |
| Molecular Formula | C30H32N2O12 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 431.5ºC | |
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Quantitative TCR:pMHC Dissociation Rate Assessment by NTAmers Reveals Antimelanoma T Cell Repertoires Enriched for High Functional Competence.
J. Immunol. 195 , 356-66, (2015) Experimental models demonstrated that therapeutic induction of CD8 T cell responses may offer protection against tumors or infectious diseases providing that T cells have sufficiently high TCR/CD8:pMHC avidity for efficient Ag recognition and consequently str... |
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Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR-Ligand Off-Rates Measurements on Living Cells.
Cancer Res. 75 , 1983-91, (2015) The avidity of the T-cell receptor (TCR) for antigenic peptides presented by the peptide-MHC (pMHC) on cells is a key parameter for cell-mediated immunity. Yet a fundamental feature of most tumor antigen-specific CD8(+) T cells is that this avidity is low. In... |
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