苯甲酰降爱康宁
苯甲酰降爱康宁结构式
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常用名 | 苯甲酰降爱康宁 | 英文名 | benzoylnorecgonine |
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| CAS号 | 41889-45-6 | 分子量 | 275.30000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C15H17NO4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Complete automation of solid-phase extraction with subsequent liquid chromatography-tandem mass spectrometry for the quantification of benzoylecgonine, m-hydroxybenzoylecgonine, p-hydroxybenzoylecgonine, and norbenzoylecgonine in urine--application to a high-throughput urine analysis laboratory.
J. Anal. Toxicol. 32(8) , 577-85, (2008) A fully automated system utilizing a liquid handler and an online solid-phase extraction (SPE) device coupled with liquid chromatography-tandem mass spectrometry (LC-MS-MS) was designed to process, detect, and quantify benzoylecgonine (BZE), meta-hydroxybenzo... |
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Simultaneous GC-MS analysis of meta- and para-hydroxybenzoylecgonine and norbenzoylecgonine: a secondary method to corroborate cocaine ingestion using nonhydrolytic metabolites.
J. Anal. Toxicol. 24(7) , 482-8, (2000) Positive benzoylecgonine (BZE) urinalysis results are sometimes challenged in legal and administrative proceedings on the grounds that the presence of BZE is due to the addition of cocaine to the urine sample with subsequent in vitro hydrolysis to BZE. Conseq... |
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Urinary excretion of ecgonine and five other cocaine metabolites following controlled oral, intravenous, intranasal, and smoked administration of cocaine.
J. Anal. Toxicol. 34(2) , 57-63, (2010) Urinary excretion of ecgonine (EC) was compared to that of cocaine, benzoylecgonine, ecgonine methyl ester and minor metabolites, meta-hydroxybenzoylecgonine, para-hydroxybenzoylecgonine, and norbenzoylecgonine, following controlled administration of oral, in... |
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Pharmacokinetics of cocaine and metabolites following intragastric administration to ten-day-old rat pups.
Pharm. Res. 15(3) , 488-91, (1998)
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In vivo pharmacokinetics and in vitro production of cocaethylene in pregnant guinea pigs.
Life Sci. 58(20) , 1695-704, (1996) Simultaneous exposure to cocaine and ethanol results in the formation of cocaethylene, an active metabolite of cocaine. The concurrent abuse of both cocaine and ethanol is common during human pregnancy, but the kinetics of elimination and formation of this et... |
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Simultaneous determination of cocaine and its metabolites with caffeine in rat serum microsamples by high-performance liquid chromatography.
J. Chromatogr. A. 532(1) , 95-103, (1990) A single, isocratic high-performance liquid chromatographic method is described for the determination of cocaine and three of its metabolites along with caffeine in serum microsamples (50 microliters). The small sample size permits the tracking of pharmacokin... |
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Effects of ethanol on cocaine metabolism: formation of cocaethylene and norcocaethylene.
Toxicol. Appl. Pharmacol. 117(1) , 1-8, (1992) The coabuse of cocaine and ethanol occurs with high frequency and increases the risk of cocaine-related morbidity and mortality. The mechanisms mediating the toxic interactions of cocaine and ethanol are not clearly defined. This study examined the effects of... |
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Microassay for the simultaneous determination of cocaine, norcocaine, benzoylecgonine and benzoylnorecgonine by high-performance liquid chromatography.
J. Chromatogr. A. 525(1) , 113-21, (1990) An improved method for the simultaneous determination of cocaine, norcocaine, benzoylecgonine and benzoylnorecgonine using reversed-phase high-performance liquid chromatography with ultraviolet detection is described. Following solid-phase extraction, chromat... |
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Quantitation of benzoylnorecgonine and other cocaine metabolites in meconium by high-performance liquid chromatography.
J. Chromatogr. A. 613(2) , 330-5, (1993) A method for simultaneous extraction of cocaine and metabolites benzoylnorecgonine, benzoylecgonine and norcocaine from meconium was developed. The procedure uses solid-phase extraction columns with both cation-exchange and hydrophobic properties after vortex... |
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Determination of cocaine and selected metabolites in canine and human serum by reversed-phase high-performance liquid chromatography on coupled cyanopropyl and silica columns.
J. Chromatogr. A. 495 , 153-65, (1989) A high-performance liquid chromatographic procedure for the determination of cocaine and selected metabolites (benzoylecgonine, norcocaine and benzoylnorecgonine) from human and canine serum has been developed. The analytes are extracted from 0.5-ml serum sam... |