ADHP
ADHP结构式
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常用名 | ADHP | 英文名 | Ampliflu Red |
|---|---|---|---|---|
| CAS号 | 119171-73-2 | 分子量 | 257.241 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 618.6±55.0 °C at 760 mmHg | |
| 分子式 | C14H11NO4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 327.9±31.5 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Human recombinant cytochrome P450 enzymes display distinct hydrogen peroxide generating activities during substrate independent NADPH oxidase reactions.
Toxicol. Sci. 141(2) , 344-52, (2014) Microsomal enzymes generate H2O2 in the presence of NADPH. In this reaction, referred to as "oxidase" activity, H2O2 is generated directly or indirectly via the formation of superoxide anion. In the presence of redox active transition metals, H2O2 can form hi... |
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Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms.
FEBS J. 281(16) , 3719-38, (2014) Accumulating evidence from in vitro, in vivo, clinical and epidemiological studies shows promising results for the use of statins against many cancers including breast carcinoma. However, the molecular mechanisms responsible for the anti-proliferative and ant... |
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Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors.
Lab Chip 15 , 2162-72, (2015) A novel, rapid and simple method for the preparation of emulsion-templated monoliths in microfluidic channels based on thiol-ene chemistry is presented. The method allows monolith synthesis and anchoring inside thiol-ene microchannels in a single photoinitiat... |
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Rapid chemiluminescent sandwich enzyme immunoassay capable of consecutively quantifying multiple tumor markers in a sample.
Talanta 129 , 106-12, (2014) Using the role of p-iodophenol in enzyme assay, enhanced 1,1'-oxalyldiimidazole chemiluminescent enzyme immunoassays (ODI-CLEIAs) were developed to consecutively quantify trace levels of triple tumor markers, such as alpha fetoprotein (AFP), carcinoembryonic ... |
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Mechanistic characterization of a 2-thioxanthine myeloperoxidase inhibitor and selectivity assessment utilizing click chemistry--activity-based protein profiling.
Biochemistry 52(51) , 9187-201, (2013) Myeloperoxidase (MPO) is a heme peroxidase that catalyzes the production of hypochlorous acid. Despite a high level of interest in MPO as a therapeutic target, there have been limited reports about MPO inhibitors that are suitable for evaluating MPO in pharma... |
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Moderate dependence of reactive oxygen species production on membrane potential in avian muscle mitochondria oxidizing glycerol 3-phosphate.
J. Physiol. Sci. 65 , 555-9, (2015) Mitochondria are a major source of reactive oxygen species production in cells, and the production level is sensitive to the magnitude of the membrane potential (ΔΨ). The present study investigated the level of superoxide production in mitochondria oxidizing ... |
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Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21-Mediated Early Senescence Signalling.
PLoS Comput. Biol. 11 , e1004246, (2015) Unrepaired or inaccurately repaired DNA damage can lead to a range of cell fates, such as apoptosis, cellular senescence or cancer, depending on the efficiency and accuracy of DNA damage repair and on the downstream DNA damage signalling. DNA damage repair an... |
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Caffeic Acid phenethyl ester: consequences of its hydrophobicity in the oxidative functions and cytokine release by leukocytes.
Evid. Based. Complement. Alternat. Med. 2014 , 793629, (2014) Numerous anti-inflammatory properties have been attributed to caffeic acid phenethyl ester (CAPE), an active component of propolis. NADPH oxidases are multienzymatic complexes involved in many inflammatory diseases. Here, we studied the importance of the CAPE... |
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Uncovering novel 3-hydroxy-4-pyridinone metal ion complexes with potential anti-inflammatory properties.
J. Inorg. Biochem. 155 , 9-16, (2015) Ligands of the 3-hydroxy-4-pyridinone (3,4-HPO) type, with one (Hmpp) or two methyl groups (Hdmpp), have been reported to possess biomedical, chemical and analytical applications. In this first screening study aiming to uncover new promising agents to mitigat... |
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Catalytic activity and thermal stability of horseradish peroxidase encapsulated in self-assembled organic nanotubes.
Analyst 141 , 2191-8, (2016) Horseradish peroxidase (HRP) was encapsulated in self-assembled lithocholic acid (LCA) based organic nanotubes and its catalytic activity before and after thermal treatment was measured for comparison with free HRP. The apparent kcat (kcat/Km) for nanotube en... |