4-氨基环己烷-1-羧酸
4-氨基环己烷-1-羧酸结构式
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常用名 | 4-氨基环己烷-1-羧酸 | 英文名 | 4-Aminocyclohexanecarboxylic acid |
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| CAS号 | 3685-23-2 | 分子量 | 143.184 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 280.0±33.0 °C at 760 mmHg | |
| 分子式 | C7H13NO2 | 熔点 | 299-301 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 123.1±25.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Opioid deltorphin C analogues containing cis- or trans-2- or 3- or 4-aminocyclohexanecarboxylic acid residues.
Arzneimittelforschung 49(1) , 6-12, (1999) The solid phase synthesis, based on the Fmoc chemical protocol, was used to prepare ten deltorphin C (Del-C; H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2) analogues containing cis- and trans- 2 or 3- or 4- aminocyclohexanecarboxylic acid (ACCA) residues at position 2.... |
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cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino] cyclohexanecarboxylic acid, a nitrosourea with latent activity against an experimental solid tumor.
J. Med. Chem. 27(1) , 97-9, (1984) cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino] cyclohexanecarboxylic acid (N-Me-cis-CCCNU) was synthesized in five steps from cis-4-aminocyclohexanecarboxylic acid via an N-tosylated intermediate. N-Me-cis-CCCNU, which is incapable of the facile d... |
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Hydrogen-bonding patterns in cis-4-ammoniocyclohexanecarboxylate hemihydrate.
Acta Crystallogr. C 60(Pt 10) , o759-61, (2004)
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Cytotoxic T lymphocyte epitope analogues containing cis- or trans-4-aminocyclohexanecarboxylic acid residues.
Bioorg. Med. Chem. 10(9) , 3061-6, (2002) In order to improve the immunotherapeutical potential of H-Cys-Leu-Gly-Gly-Leu-Leu-Thr-Met-Val-OH (CLG) peptide, an Epstein-Barr virus (EBV) subdominant epitope derived from the membrane protein LMP2, we have synthesized and tested CLG analogues containing ci... |
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Influence of conformationally constrained amino acids replacing positions 2 and 3 of arginine vasopressin (AVP) and its analogues on their pharmacological properties.
Protein Pept. Lett. 14(3) , 213-7, (2007) Synthesis of thirteen new analogues of arginine vasopressin (AVP) has been described. Amino acid residues at positions 2 and 3 of AVP, [3-mercaptopropionic acid (Mpa)(1)]AVP (dAVP), [Mpa(1),d-Arg(8)]VP (dDAVP) and [Mpa(1),Val(4),d-Arg(8)]VP (dVDAVP) were repl... |
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Thrombin-induced alterations in lung fluid balance in awake sheep.
J. Appl. Physiol. 58(5) , 1421-7, (1985) We examined the effect of fibrinolysis depression on thrombin-induced pulmonary microembolism in awake sheep prepared with chronic lung lymph fistulas. Fibrinolysis was depressed by an intravenous infusion (100 mg) of tranexamic acid [trans-4-(Aminomethyl)cyc... |
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GABA analogues derived from 4-aminocyclopent-1-enecarboxylic acid.
Neurochem. Res. 34(10) , 1698-703, (2009) The incorporation of extra binding groups onto known ligands is a powerful tool for the development of more potent and selective agents at target sites such as the GABA receptors. In the present work we have attempted to build on the activity of the know pote... |