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邻甲基苯乙酸

邻甲基苯乙酸结构式
邻甲基苯乙酸结构式
品牌特惠专场
常用名 邻甲基苯乙酸 英文名 o-Tolylacetic acid
CAS号 644-36-0 分子量 150.174
密度 1.1±0.1 g/cm3 沸点 279.3±9.0 °C at 760 mmHg
分子式 C9H10O2 熔点 88-90 °C(lit.)
MSDS 中文版 美版 闪点 176.5±13.9 °C
符号 GHS07
GHS07
信号词 Warning

Abnormal excitability and episodic low-frequency oscillations in the cerebral cortex of the tottering mouse.

J. Neurosci. 35(14) , 5664-79, (2015)

The Ca(2+) channelopathies caused by mutations of the CACNA1A gene that encodes the pore-forming subunit of the human Cav2.1 (P/Q-type) voltage-gated Ca(2+) channel include episodic ataxia type 2 (EA2). Although, in EA2 the emphasis has been on cerebellar dys...

Homer protein-metabotropic glutamate receptor binding regulates endocannabinoid signaling and affects hyperexcitability in a mouse model of fragile X syndrome.

J. Neurosci. 35(9) , 3938-45, (2015)

The Fmr1 knock-out mouse model of fragile X syndrome (Fmr1(-/y)) has an epileptogenic phenotype that is triggered by group I metabotropic glutamate receptor (mGluR) activation. We found that a membrane-permeable peptide that disrupts mGluR5 interactions with ...

Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells.

J. Neurosci. 35 , 15837-46, (2015)

The endoplasmic reticulum (ER) plays crucial roles in intracellular Ca(2+) signaling, serving as both a source and sink of Ca(2+), and regulating a variety of physiological and pathophysiological events in neurons in the brain. However, spatiotemporal Ca(2+) ...