MCLA盐酸盐
MCLA盐酸盐结构式
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常用名 | MCLA盐酸盐 | 英文名 | MCLA hydrochloride |
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| CAS号 | 128322-44-1 | 分子量 | 291.733 | |
| 密度 | N/A | 沸点 | 410.3ºC at 760 mmHg | |
| 分子式 | C14H14ClN3O2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 201.9ºC |
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Endothelial Angiogenesis and Barrier Function in Response to Thrombin Require Ca2+ Influx through the Na+/Ca2+ Exchanger.
J. Biol. Chem. 290 , 18412-28, (2015) Thrombin acts on the endothelium by activating protease-activated receptors (PARs). The endothelial thrombin-PAR system becomes deregulated during pathological conditions resulting in loss of barrier function and a pro-inflammatory and pro-angiogenic endothel... |
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A sensitive and specific chemiluminescence method for estimating the ability of human granulocytes and monocytes to generate O2-.
Clin. Chim. Acta 179 , 177, (1989)
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The first observation of O2- generation in in situ lungs of rats treated with drugs to induce experimental acute respiratory distress syndrome.
FEBS Lett. 261 , 369, (1990) To investigate O2- generation in in situ lungs of rats treated with drugs to induce experimental acute respiratory distress syndrome, phorbol myristate acetate (PMA) or endotoxin were injected into rats, who had been continuously infused with 2(methyl-6-[p-me... |
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Mechanism for the generation of superoxide anion and singlet oxygen during heme compound-catalyzed linoleic acid hydroperoxide decomposition.
Arch. Biochem. Biophys. 289 , 223, (1991) Heme compound, hematin or cytochrome c, catalyzes the decomposition of 13-hydroperoxy linoleic acid yielding both O2- and 1O2 under aerobic conditions. No 1O2 is produced when hydrogen peroxide and cumene hydroperoxide are used as substrates. In these experim... |
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Uncovering novel 3-hydroxy-4-pyridinone metal ion complexes with potential anti-inflammatory properties.
J. Inorg. Biochem. 155 , 9-16, (2015) Ligands of the 3-hydroxy-4-pyridinone (3,4-HPO) type, with one (Hmpp) or two methyl groups (Hdmpp), have been reported to possess biomedical, chemical and analytical applications. In this first screening study aiming to uncover new promising agents to mitigat... |
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Endurance exercise and conjugated linoleic acid (CLA) supplementation up-regulate CYP17A1 and stimulate testosterone biosynthesis.
PLoS ONE 8 , e79686, (2013) A new role for fat supplements, in particular conjugated linoleic acid (CLA), has been delineated in steroidogenesis, although the underlying molecular mechanisms have not yet been elucidated. The aims of the present study were to identify the pathway stimula... |
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Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation.
J. Clin. Biochem. Nutr. 41 , 68-75, (2008) We have proposed that diacylglycerol hydroperoxide-induced unregulated signal transduction causes oxidative stress-related diseases. In this study, we investigated which molecular species of diacylglycerol hydroperoxide activated human peripheral neutrophils.... |
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Potent radical-scavenging activities of thiamin and thiamin diphosphate.
J. Clin. Biochem. Nutr. 40 , 42-8, (2008) Various radical-scavenging activities of thiamin and thiamin diphosphate (TDP) were found in some in vitro experiments. Thiamin and TDP caused considerable suppressive effects on superoxide generation in hypoxanthine and xanthine oxidase system which was meas... |