异丙基异氰
异丙基异氰结构式
|
常用名 | 异丙基异氰 | 英文名 | Isopropyl isocyanide |
|---|---|---|---|---|
| CAS号 | 598-45-8 | 分子量 | 69.10510 | |
| 密度 | 0.733 g/mL at 25ºC(lit.) | 沸点 | 75ºC(lit.) | |
| 分子式 | C4H7N | 熔点 | N/A | |
| MSDS | 中文版 | 闪点 | 69 °F | |
| 符号 |
GHS02, GHS06 |
信号词 | Danger |
|
Isocyanides inhibit human heme oxygenases at the verdoheme stage.
Biochemistry 48(37) , 8920-8, (2009) Heme oxygenases (HO) catalyze the oxidative cleavage of heme to generate biliverdin, CO, and free iron. In humans, heme oxygenase-1 (hHO-1) is overexpressed in tumor tissues, where it helps to protect cancer cells from anticancer agents, while HOs in fungal p... |
|
|
The reaction of trout hemoglobins with isocyanides.
Eur. J. Biochem. 135(1) , 171-4, (1983) Binding of alkylisocyanides of different bulkiness to the two major components of trout hemolysate is presented. In the case of trout hemoglobin I isocyanide binding is pH-independent, similar to O2 and CO, and the bulkiness of the ligand is related to the en... |
|
|
Isocyanide binding to the copper(I) centers of the catalytic core of peptidylglycine monooxygenase (PHMcc).
J. Biol. Inorg. Chem. 6(5-6) , 567-77, (2001) Binding of the Cu(I)-specific ligands 2,6-dimethylphenyl isocyanide (DIMPI) and isopropyl isocyanide (IPI) to the reduced form of peptidylglycine monooxygenase (PHM) is reported. Both ligands bind to the methionine-containing CuM center, eliciting FTIR bands ... |