4-环戊烯-1,3-二酮
4-环戊烯-1,3-二酮结构式
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常用名 | 4-环戊烯-1,3-二酮 | 英文名 | 2-Cyclopentene-1,4-dione |
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| CAS号 | 930-60-9 | 分子量 | 96.084 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 226.3±0.0 °C at 760 mmHg | |
| 分子式 | C5H4O2 | 熔点 | 34-36ºC(lit.) | |
| MSDS | 美版 | 闪点 | 83.9±0.0 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes.
J. Immunol. 194(6) , 2776-85, (2015) Inflammasomes are cytosolic protein complexes that respond to diverse danger signals by activating caspase-1. The sensor components of the inflammasome, often proteins of the nucleotide-binding oligomerization domain-like receptor (NLR) family, detect stress,... |
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SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors.
J. Med. Chem. 48 , 7103-12, (2005) The 2,4-disubstituted thiadiazolidinones (TDZD) are described as the first ATP-noncompetitive GSK-3 inhibitors. Following an SAR study about TDZD, different structural modifications in the heterocyclic ring aimed to test the influence of each heteroatom on th... |
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Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins.
Chem. Commun. (Camb.) 47(32) , 9203-5, (2011) Facile, two-step synthesis and kinetic characterization of new chemical probes for selective labeling of sulfenic acid (-SOH) in proteins are presented. The synthesis route relies on the simple and highly efficient Michael addition of thiol containing tags or... |
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Antifungal acylcyclopentenediones from fruiting bodies of Hygrophorus chrysodon.
J. Nat. Prod. 70(1) , 137-9, (2007) Chrysotriones A (1) and B (2), two new 2-acylcyclopentene-1,3-dione derivatives, were isolated from the fruiting bodies of the Basidiomycete Hygrophorus chrysodon, and their structures were established by spectroscopic data and synthesis of compound 2. They r... |
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Purification and characterization of two phospholipid exchange proteins from bovine heart.
J. Biol. Chem. 254(16) , 7795-802, (1979) Two phospholipid exchange proteins from bovine heart have been purified approximately 2000-fold and judged greater than 90% pure. The proteins are similar in molecular weight (both 33,400 by polyacrylamide gel electrophoresis and 23,500 by gel filtration), in... |
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Design of antiangiogenic hypoxic cell radiosensitizers: 2-nitroimidazoles containing a 2-aminomethylene-4-cyclopentene-1,3-dione moiety.
Bioorg. Med. Chem. 16(11) , 6042-53, (2008) We designed chiral 2-nitroimidazole derivatives containing a 2-aminomethylene-4-cyclopentene-1,3-dione moiety as antiangiogenic hypoxic cell radiosensitizers. Based on results of molecular orbital calculations, the 2-aminomethylene-4-cyclopentene-1,3-dione mo... |
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Effects of cyclopentenone prostaglandins and related compounds on insulin-like growth factor-I and Waf1 gene expression.
Biochim. Biophys. Acta 1397(1) , 31-42, (1998) The molecular pathways by which the cyclopentenone prostaglandins (PGA and PGJ series) inhibit cell growth and tumorigenicity are poorly understood. These cellular responses may be caused by specific regulation of growth-related and stress-induced genes. A va... |
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Sulfhydryl alkylating agents induce calcium current in skeletal muscle fibers of a crustacean (Atya lanipes).
J. Membr. Biol. 129(2) , 167-78, (1992) Voltage-clamp experiments using the three-microelectrode voltage clamp technique were performed on ventroabdominal flexor muscles of the crustacean Atya lanipes. Potassium and chloride currents were found to underlie the normal, passive response of the muscle... |
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Cavity ringdown spectrum of the T(1)(n,pi*) <-- S(0) transition of 4-cyclopentene-1,3-dione.
J. Phys. Chem. A 113(47) , 13318-26, (2009) The cavity ringdown absorption spectrum of 4-cyclopentene-1,3-dione was recorded near 487 nm in a room-temperature gas cell. The very weak band system (epsilon approximately 0.05 dm3 mol-1 cm-1) in this region is due to the T1(n,pi*) <-- S0 electronic transit... |