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紫色杆菌素

紫色杆菌素结构式
紫色杆菌素结构式
品牌特惠专场
常用名 紫色杆菌素 英文名 Violacein
CAS号 548-54-9 分子量 343.34
密度 1.549g/cm3 沸点 821.4ºC at 760mmHg
分子式 C20H13N3O3 熔点 N/A
MSDS 中文版 美版 闪点 450.6ºC

The impact of plant volatiles on bacterial quorum sensing.

Lett. Appl. Microbiol. 60(1) , 8-19, (2015)

Studies describing the use of essential oil constituents as antimicrobial agents have steadily increased; however, some phyto-constituents are often overlooked due to unfavourable minimum inhibitory concentration (MIC) values. Virulence depends on transcripti...

Isolation of natural products by ion-exchange methods.

Methods Mol. Biol. 864 , 189-219, (2012)

The primary goal of many natural products chemists is to extract, isolate, and characterize specific analytes from complex plant, animal, microbial, and food matrices. To achieve this goal, they rely considerably on highly sophisticated and highly hyphenated ...

Crystalline xylitol production by a novel yeast, Pichia caribbica (HQ222812), and its application for quorum sensing inhibition in gram-negative marker strain Chromobacterium violaceum CV026.

Appl. Biochem. Biotechnol. 169(6) , 1753-63, (2013)

Xylitol, a sugar alcohol, is fast gaining ground over other artificial sugar substitutes owing to its advantageous properties. Xylitol is a safer alternative for diabetics because of insulin-independent metabolism. It has beneficial properties suitable to for...

Hematopoietic modulators as potential agents for the treatment of leukemia.

Front. Biosci. (Elite Ed.) 5 , 130-40, (2013)

Leukemias are the most common malignancy of childhood and have the highest mortality among aging people. Leukemias are a group of blood disorders characterized by an accumulation of leukemic cells in the peripheral blood of patients as a result of disturbance...

Tandem ring-closing metathesis/isomerization reactions for the total synthesis of violacein.

Org. Lett. 15(8) , 1986-9, (2013)

A series of 5-substituted 2-pyrrolidinones was synthesized through a one-pot ruthenium alkylidene-catalyzed tandem RCM/isomerization/nucleophilic addition sequence. The intermediates resulting from RCM/isomerization showed reactivity toward electrophiles in a...

Coupling reaction of indolepyruvic acid by StaD and its product: implications for biosynthesis of indolocarbazole and violacein.

ChemBioChem. 13(17) , 2495-500, (2012)

Design, synthesis and biological evaluation of N-sulfonyl homoserine lactone derivatives as inhibitors of quorum sensing in Chromobacterium violaceum.

Molecules 18(3) , 3266-78, (2013)

A novel series of N-sulfonyl homoserine lactone derivatives 5a-l has been designed, synthesized and evaluated for quorum sensing inhibitory activities towards violacein production. Of the compounds synthesized, compound 5h was found to possess an excellent le...

Attenuation of Pseudomonas aeruginosa virulence by marine invertebrate-derived Streptomyces sp.

Lett. Appl. Microbiol. 56(3) , 197-207, (2013)

The study aimed to discover quorum sensing (QS) inhibitors from marine sponge-derived actinomycetes and analyse its inhibitory activities against QS-mediated virulence factors in Pseudomonas aeruginosa. Seventy-two actinomycetes isolated from marine invertebr...

Characterization of a gene cluster and its putative promoter region for violacein biosynthesis in Pseudoalteromonas sp. 520P1.

Appl. Microbiol. Biotechnol. 90(6) , 1963-71, (2011)

Violacein, a purple pigment produced by some Gram-negative bacteria, has various physiological properties, such as antitrypanosomal and antitumoral activities. A gene cluster that encodes five enzymes, VioA-VioE, is responsible for synthesizing violacein. The...

Amphypterygium adstringens anacardic acid mixture inhibits quorum sensing-controlled virulence factors of Chromobacterium violaceum and Pseudomonas aeruginosa.

Arch. Med. Res. 44(7) , 488-94, (2013)

Quorum sensing (QS) is a process of bacterial cell-cell communication that controls a large number of systems affecting pathogenicity. Interrupting this communication system can provide nonvirulent pathogenic bacteria. The aim of this study was to evaluate th...