碳酸酐酶 来源于牛红细胞
碳酸酐酶 来源于牛红细胞结构式
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常用名 | 碳酸酐酶 来源于牛红细胞 | 英文名 | Carbonic anhydrase |
|---|---|---|---|---|
| CAS号 | 9001-03-0 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Local pH domains regulate NHE3-mediated Na⁺ reabsorption in the renal proximal tubule.
Am. J. Physiol. Renal Physiol. 307(11) , F1249-62, (2014) The proximal tubule Na(+)/H(+) exchanger 3 (NHE3), located in the apical dense microvilli (brush border), plays a major role in the reabsorption of NaCl and water in the renal proximal tubule. In response to a rise in blood pressure NHE3 redistributes in the ... |
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Short peptides self-assemble to produce catalytic amyloids.
Nature Chemistry 6(4) , 303-9, (2014) Enzymes fold into unique three-dimensional structures, which underlie their remarkable catalytic properties. The requirement to adopt a stable, folded conformation is likely to contribute to their relatively large size (>10,000 Da). However, much shorter pept... |
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Crystal structures of two tetrameric β-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora.
FEBS J. 281(7) , 1759-72, (2014) Carbonic anhydrases (CAs) are metalloenzymes catalyzing the reversible hydration of carbon dioxide to bicarbonate (hydrogen carbonate) and protons. CAs have been identified in archaea, bacteria and eukaryotes and can be classified into five groups (α, β, γ, δ... |
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Designing hydrolytic zinc metalloenzymes.
Biochemistry 53(6) , 957-78, (2014) Zinc is an essential element required for the function of more than 300 enzymes spanning all classes. Despite years of dedicated study, questions regarding the connections between primary and secondary metal ligands and protein structure and function remain u... |
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Reply to Morel: Cadmium as a micronutrient and macrotoxin in the oceans.
Proc. Natl. Acad. Sci. U. S. A. 110(21) , E1878, (2013)
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The oceanic cadmium cycle: biological mistake or utilization?
Proc. Natl. Acad. Sci. U. S. A. 110(21) , E1877, (2013)
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Proteomic analysis of skeletal organic matrix from the stony coral Stylophora pistillata.
Proc. Natl. Acad. Sci. U. S. A. 110(10) , 3788-93, (2013) It has long been recognized that a suite of proteins exists in coral skeletons that is critical for the oriented precipitation of calcium carbonate crystals, yet these proteins remain poorly characterized. Using liquid chromatography-tandem mass spectrometry ... |
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4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.
Bioorg. Med. Chem. 21(7) , 2093-106, (2013) A series of 4-substituted-2,3,5,6-tetrafluorobenezenesulfonamides were synthesized and their binding potencies as inhibitors of recombinant human carbonic anhydrase isozymes I, II, VII, XII, and XIII were determined by the thermal shift assay, isothermal titr... |
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Targeted mutagenesis of mitochondrial carbonic anhydrases VA and VB implicates both enzymes in ammonia detoxification and glucose metabolism.
Proc. Natl. Acad. Sci. U. S. A. 110(18) , 7423-8, (2013) Prior studies with carbonic anhydrase (CA) inhibitors implicated mitochondrial CA in ureagenesis and gluconeogenesis. Subsequent studies identified two mitochondrial CAs. To distinguish the contribution of each enzyme, we studied the effects of targeted disru... |
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Prognostic significance of HIF-1a, CA-IX, and OPN in T1-T2 laryngeal carcinoma treated with radiotherapy.
Laryngoscope 123(9) , 2154-60, (2013) To examine the prognostic value of hypoxia inducible factor HIF-1a, CA-IX, and OPN on clinical outcome in patients with T1-T2 supraglottic laryngeal squamous cell carcinoma (LSCC) treated with primarily radiotherapy (RT).Retrospective cohort study.Tumor tissu... |