2-正辛基-4-异噻唑啉-3-酮
2-正辛基-4-异噻唑啉-3-酮结构式
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常用名 | 2-正辛基-4-异噻唑啉-3-酮 | 英文名 | 2-Octyl-2H-isothiazol-3-one |
|---|---|---|---|---|
| CAS号 | 26530-20-1 | 分子量 | 213.340 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 304.5±25.0 °C at 760 mmHg | |
| 分子式 | C11H19NOS | 熔点 | 23 °C | |
| MSDS | 中文版 美版 | 闪点 | 137.9±23.2 °C | |
| 符号 |
GHS05, GHS06, GHS09 |
信号词 | Danger |
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Contact dermatitis from 2-n-octyl-4-isothiazolin-3-one in a PhD student.
Contact Dermatitis 50(1) , 47-8, (2004)
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Allergic contact dermatitis from 2-n-octyl-4-isothiazolin-3-one, a paint mildewcide.
Contact Dermatitis 9(6) , 507-9, (1983) Severe allergic contact dermatitis from a paint mildewcide, 2-n-octyl-4-isothiazolin-3-one, developed in a worker formulating latex paints within a paint manufacturing company, Guinea pig maximization testing demonstrated this to be a moderate sensitizer. Fur... |
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[Allergic contact eczema caused by isothiazolin-3-one derivatives].
Derm. Beruf Umwelt. 32(6) , 208-11, (1984) Observations concerning contact dermatitis to derivatives of isothiazolin-3-one are reported. A systematic review of the literature of previously published cases is reported. A verified contact dermatitis to benzisothiazolin-3-one of a laborer in a rubber fac... |
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A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone-based enzyme inhibitors.
Br. J. Pharmacol. 157(6) , 974-83, (2009) Monoacylglycerol lipase (MGL) is a presynaptic serine hydrolase that inactivates the endocannabinoid neurotransmitter, 2-arachidonoyl-sn-glycerol. Recent studies suggest that cysteine residues proximal to the enzyme active site are important for MGL function.... |
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Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone.
Bioorg. Med. Chem. Lett. 21(24) , 7321-4, (2011) The regulation of 2-arachidonoylglycerol (2-AG) levels is a major issue as 2-AG has been proven to participate in numerous physiopathological phenomena such as neuroprotection or analgesia. Octhilinone, a cysteine-reagent compound, has recently been shown to ... |
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The irritancy and allergenicity of 2-n-octyl-4-isothiazolin-3-one (Skane M-8), with recommendations for patch test concentration.
Contact Dermatitis 20(1) , 21-6, (1989) Preparations of 2-n-octyl-4-isothiazolin-3-one (Skane M-8) at 1000 p.p.m. a.i. and 500 p.p.m. a.i. in pet. induced allergy in a cumulative insult human patch test. Challenge patch testing using 250 p.p.m. a.i. Skane M-8 elicited allergy in 6 out of 6 sensitiz... |
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Occupational allergic contact dermatitis from 2-N-octyl-4-isothiazolin-3-one.
Contact Dermatitis 56(3) , 160-3, (2007) 2-N-octyl-4-isothiazolin-3-one (OIT) is an antimicrobial agent that is mainly used in industrial settings. The objective of the study was to find the significance of OIT contact allergy at our clinic of occupational dermatology. We looked through our patient ... |
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Allergic contact dermatitis from Kathon 893.
Contact Dermatitis 27(5) , 345-6, (1992)
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Fungal colonization of soil-buried plasticized polyvinyl chloride (pPVC) and the impact of incorporated biocides.
Microbiology 152(Pt 6) , 1731-9, (2006) Plasticized polyvinyl chloride (pPVC) with or without incorporated biocides was buried in grassland and forest soil for up to 10 months. The change with time in viable counts of fungi on the plastic surface was followed, together with the percentage capable o... |
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Rolling--a new application technique for luminescent bacteria on high-performance thin-layer chromatography plates.
J. Chromatogr. A. 1218(19) , 2692-9, (2011) High-performance thin-layer chromatography (HPTLC) coupled with bioluminescence detection using Vibrio fischeri bacteria can be used for screening for unknown substances. This is accomplished by dipping the HPTLC plate in an aqueous bacteria solution. Especia... |