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3-硝基苯磺酰氯

一般危化品
3-硝基苯磺酰氯结构式
3-硝基苯磺酰氯结构式
常用名 3-硝基苯磺酰氯 英文名 3-Nitrophenylsulfonyl chloride
CAS号 121-51-7 分子量 221.618
密度 1.6±0.1 g/cm3 沸点 341.0±25.0 °C at 760 mmHg
分子式 C6H4ClNO4S 熔点 61-62 °C(lit.)
MSDS 中文版 美版 闪点 160.0±23.2 °C
符号 GHS05
GHS05
信号词 Danger

Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.

Bioorg. Med. Chem. 15(1) , 403-12, (2007)

3-{1-[(4-Fluorophenyl)sulfonyl]-1H-pyrazol-3-yl}-2-methylimidazo[1,2-a]pyridine, 2a, was discovered in our chemical library as a novel p110alpha inhibitor with an IC(50) of 0.67microM, through screening in a scintillation proximity assay. Optimization of the ...

Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.

Bioorg. Med. Chem. Lett. 16 , 2842-2845, (2006)

High-throughput screening of a small-molecule compound library resulted in the identification of a novel series of N-acyl 2-aminobenzimidazoles that are potent inhibitors of interleukin-1 receptor-associated kinase-4.