苯吡烯胺二盐酸盐(一水)
苯吡烯胺二盐酸盐(一水)结构式
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常用名 | 苯吡烯胺二盐酸盐(一水) | 英文名 | ZIMELIDINE 2HCL |
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| CAS号 | 61129-30-4 | 分子量 | 317.22400 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C16H17BrN2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Activation and desensitization by cyclic antidepressant drugs of alpha2-autoreceptors, alpha2-heteroreceptors and 5-HT1A-autoreceptors regulating monamine synthesis in the rat brain in vivo.
Naunyn Schmiedebergs Arch. Pharmacol. 360 , 135-143, (1999) The effects of antidepressant drugs on the synthesis of noradrenaline and serotonin (5-HT) were assessed using the accumulation of 3,4-dihydroxyphenylalanine (dopa) and 5-hydroxytryptophan (5-HTP) after decarboxylase inhibition as a measure of the rate of tyr... |
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Serotonin uptake inhibitors: uses in clinical therapy and in laboratory research.
Fortschr. Arzneimittelforsch. 45 , 167-204, (1995) Fluoxetine, zimelidine, sertraline, paroxetine, fluvoxamine, indalpine and citalopram are the selective inhibitors of serotonin uptake that have been most widely studied. Some of these compounds are or have been used clinically in the treatment of mental depr... |
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The inhibition of monoamine oxidase activity by various antidepressants: differences found in various mammalian species.
Jpn. J. Pharmacol. 81 , 115-121, (1999) The effects of the antidepressant drugs zimeldine, imipramine, maprotiline or nomifensine on mitochondrial monoamine oxidase (MAO) activity in mouse, rat, dog and monkey brains were compared in vitro. Mouse, rat, dog and monkey brain MAO-B activities were inh... |
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Neonatal treatments with the serotonin uptake inhibitors clomipramine and zimelidine, but not the noradrenaline uptake inhibitor desipramine, disrupt sleep patterns in adult rats.
Brain Res. 768 , 287-293, (1997) Chronic postnatal exposure to clomipramine (CMI), a monoamine uptake inhibitor, results in persistent alterations in adult rat REM sleep. These effects have been ascribed to CMI's ability to block neonatal active sleep (AS). However, these effects have not be... |