多聚-D-赖氨酸氢溴酸盐
多聚-D-赖氨酸氢溴酸盐结构式
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常用名 | 多聚-D-赖氨酸氢溴酸盐 | 英文名 | Poly-D-lysine hydrobromide (MW 30000-70000) |
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| CAS号 | 27964-99-4 | 分子量 | 30000-70000 | |
| 密度 | N/A | 沸点 | 343.7±0.0 °C at 760 mmHg | |
| 分子式 | (C6H14N2O2)x.xBrH | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 161.7±0.0 °C |
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Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy.
Breast Cancer Res. 17 , 19, (2015) Targeted therapies for aggressive breast cancers like triple negative breast cancer (TNBC) are needed. The use of small interfering RNAs (siRNAs) to disable expression of survival genes provides a tool for killing these cancer cells. Cyclin dependent kinase 1... |
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Stochastic Micro-Pattern for Automated Correlative Fluorescence - Scanning Electron Microscopy.
Sci. Rep. 5 , 17973, (2015) Studies of cellular surface features gain from correlative approaches, where live cell information acquired by fluorescence light microscopy is complemented by ultrastructural information from scanning electron micrographs. Current approaches to spatially ali... |
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Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans.
Nat. Commun. 5 , 5485, (2014) The small ubiquitin-like modifier (SUMO), initially characterized as a suppressor of a mutation in the gene encoding the centromeric protein MIF2, is involved in many aspects of cell cycle regulation. The dynamics of conjugation and deconjugation and the role... |
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Schwann Cell Contact Guidance versus Boundary -Interaction in Functional Wound Healing along Nano and Microstructured Membranes.
Adv. Healthc. Mater. 4 , 1849-60, (2015) Peripheral nerve transection is often encountered after trauma and can lead to long-term/permanent loss of sensor/motor functionality. Here, the effect of pure contact interaction of nano/microgrooved substrates on Schwann cells (SCs) is studied in view of th... |
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AMPA receptor desensitization is the determinant of AMPA receptor mediated excitotoxicity in purified retinal ganglion cells.
Exp. Eye Res. 132 , 136-50, (2015) The ionotropic glutamate receptors (iGLuR) have been hypothesized to play a role in neuronal pathogenesis by mediating excitotoxic death. Previous studies on iGluR in the retina have focused on two broad classes of receptors: NMDA and non-NMDA receptors inclu... |
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Numb is required to prevent p53-dependent senescence following skeletal muscle injury.
Nat. Commun. 6 , 8528, (2015) Regeneration relies on coordinated action of multiple cell types to reconstitute the damaged tissue. Here we inactivate the endocytic adaptor protein Numb in skeletal muscle stem cells prior to chronic or severe muscle injury in mice. We observe two types of ... |
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Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs.
Exp. Cell Res. 333(1) , 21-38, (2015) LC3, a mammalian homologue of yeast Atg8, is assumed to play an important part in bulk sequestration and degradation of cytoplasm (macroautophagy), and is widely used as an indicator of this process. To critically examine its role, we followed the autophagic ... |
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Differential roles of the mevalonate pathway in the development and survival of mouse Purkinje cells in culture.
Mol. Neurobiol. 51 , 1116-29, (2015) The cerebellum is an important locus for motor learning and higher cognitive functions, and Purkinje cells constitute a key component of its circuit. Biochemically, significant turnover of cholesterol occurs in Purkinje cells, causing the activation of the me... |
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Cellular and molecular characterization of human cardiac stem cells reveals key features essential for their function and safety.
Stem Cells Dev. 24 , 1390-404, (2015) Cell therapy of heart diseases is emerging as one of the most promising known treatments in recent years. Transplantation of cardiac stem cells (CSCs) may be one of the best strategies to cure adult or pediatric heart diseases. As these patient-derived stem c... |
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Efficient transfection of dissociated mouse chromaffin cells using small-volume electroporation.
Cytotechnology 67(3) , 573-83, (2015) We have developed an improved procedure for isolating and transfecting a chromaffin cell-enriched population of primary cells from adult mouse adrenal glands. Significantly, the parameters of a novel electroporation transfection technique were optimized to ac... |