艾塞那肽
艾塞那肽结构式
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常用名 | 艾塞那肽 | 英文名 | Exendin-3 trifluoroacetate salt |
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| CAS号 | 130357-25-4 | 分子量 | 4202.57 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C184H282N50O61S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas.
J. Biol. Chem. 267 , 7402, (1992) The recent identification in Heloderma horridum venom of exendin-3, a new member of the glucagon superfamily that acts as a pancreatic secretagogue, prompted a search for a similar peptide in Heloderma suspectum venom. An amino acid sequencing assay for pepti... |
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Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line.
J. Clin. Invest. 101 , 1334-1341, (1998) To examine the influence of the putative satiety factor (GLP-1) on the hypothalamo-pituitary-gonadal axis, we used GT1-7 cells as a model of neuronal luteinizing hormone- releasing hormone (LHRH) release. GLP-1 caused a concentration-dependent increase in LHR... |
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Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function.
Diabetes 55(12) , 3463-9, (2006) In previous studies, glucagon receptor knockout mice (Gcgr(-/-)) display reduced blood glucose and increased glucose tolerance, with hyperglucagonemia and increased levels of glucagon-like peptide (GLP)-1. However, the role of glucagon receptor signaling for ... |
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Purification and structure of exendin-3, a new pancreatic secretagogue isolated from Heloderma horridum venom.
J. Biol. Chem. 265(33) , 20259-62, (1990) An amino-terminal histidyl structure (His1) is characteristic of most peptides in the glucagon superfamily. An assay for His1 peptides performed by amino-terminal amino acid sequencing was used to screen venom from the Gila monster lizard, Heloderma horridum.... |
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Actions of Helodermatidae venom peptides and mammalian glucagon-like peptides on gastric chief cells. Rai, A., et al.
Am. J. Physiol. 265 , (1993)
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Bioactive peptides from lizard venoms.
Regul. Pept. 61 , 1, (1996)
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