N-(3-(3-(哌啶-1-基甲基)苯氧基)丙基)苯并[D]噻唑-2-胺 二马来酸盐
![N-(3-(3-(哌啶-1-基甲基)苯氧基)丙基)苯并[D]噻唑-2-胺 二马来酸盐结构式](https://image.chemsrc.com/caspic/139/104076-39-3.png)
N-(3-(3-(哌啶-1-基甲基)苯氧基)丙基)苯并[D]噻唑-2-胺 二马来酸盐结构式
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常用名 | N-(3-(3-(哌啶-1-基甲基)苯氧基)丙基)苯并[D]噻唑-2-胺 二马来酸盐 | 英文名 | Zolantidine dimaleate |
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| CAS号 | 104076-39-3 | 分子量 | 613.68 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C30H35N3O9S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist.
Br. J. Pharmacol. 93(1) , 69-78, (1988) 1. The novel benzthiazole derivative zolantidine (SK&F 95282) is a potent antagonist of histamine at H2-receptors in guinea-pig atrium and rat uterus. Only apparent pA2 values of 7.46 and 7.26 respectively could be calculated since the slopes of the Schild pl... |
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Linking solubility and permeability assays for maximum throughput and reproducibility.
J. Biomol. Screen. 10(4) , 383-90, (2005) Solubility and permeability are intimately linked in drug absorption processes. They have, however, been traditionally assayed separately. To support this linkage, a combined solubility/permeability assay was developed for determining absorption properties of... |
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Identification of novel functional inhibitors of acid sphingomyelinase.
PLoS ONE 6 , e23852, (2011) We describe a hitherto unknown feature for 27 small drug-like molecules, namely functional inhibition of acid sphingomyelinase (ASM). These entities named FIASMAs (Functional Inhibitors of Acid SphingoMyelinAse), therefore, can be potentially used to treat di... |