β-淀粉样肽(1-38)(Aβ38)
β-淀粉样肽(1-38)(Aβ38)结构式
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常用名 | β-淀粉样肽(1-38)(Aβ38) | 英文名 | Amyloid β-Protein (1-38) trifluoroacetate salt |
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| CAS号 | 131438-74-9 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C184H277N51O56S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity.
J. Neurosci. 12 , 376-389, (1992) In Alzheimer's disease (AD), abnormal accumulations of beta-amyloid are present in the brain and degenerating neurons exhibit cytoskeletal aberrations (neurofibrillary tangles). Roles for beta-amyloid in the neuronal degeneration of AD have been suggested bas... |
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Morphology and antibody recognition of synthetic beta-amyloid peptides.
J. Neurosci. Res. 28 , 474-485, (1991) To elucidate the relationship between amyloid fibril formation in Alzheimer disease (AD) and the primary structure of the beta-amyloid protein (beta-AP), we investigated the ability of peptides sharing sequences with beta-AP to form fibrils in vitro and to re... |
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beta-Amyloid induction of gelatinase B secretion in cultured microglia: inhibition by dexamethasone and indomethacin.
Neuroreport 7 , 3077-3080, (1996) Since administration of anti-inflammatory drugs has been reported to possibly slow the progression of Alzheimer's disease, an effort was made to define effector functions induced by beta-amyloid (A beta) which may be inhibited by these drugs. Rat microglia in... |