Amyloid β-Protein (1-38) trifluoroacetate salt

Amyloid β-Protein (1-38) trifluoroacetate salt Structure
Amyloid β-Protein (1-38) trifluoroacetate salt structure
Common Name Amyloid β-Protein (1-38) trifluoroacetate salt
CAS Number 131438-74-9 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C184H277N51O56S Melting Point N/A
MSDS USA Flash Point N/A

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity.

J. Neurosci. 12 , 376-389, (1992)

In Alzheimer's disease (AD), abnormal accumulations of beta-amyloid are present in the brain and degenerating neurons exhibit cytoskeletal aberrations (neurofibrillary tangles). Roles for beta-amyloid in the neuronal degeneration of AD have been suggested bas...

Morphology and antibody recognition of synthetic beta-amyloid peptides.

J. Neurosci. Res. 28 , 474-485, (1991)

To elucidate the relationship between amyloid fibril formation in Alzheimer disease (AD) and the primary structure of the beta-amyloid protein (beta-AP), we investigated the ability of peptides sharing sequences with beta-AP to form fibrils in vitro and to re...

beta-Amyloid induction of gelatinase B secretion in cultured microglia: inhibition by dexamethasone and indomethacin.

Neuroreport 7 , 3077-3080, (1996)

Since administration of anti-inflammatory drugs has been reported to possibly slow the progression of Alzheimer's disease, an effort was made to define effector functions induced by beta-amyloid (A beta) which may be inhibited by these drugs. Rat microglia in...