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2,4-二甲基苯酚

一般危化品
2,4-二甲基苯酚结构式
2,4-二甲基苯酚结构式
常用名 2,4-二甲基苯酚 英文名 2,4-xylenol
CAS号 105-67-9 分子量 122.164
密度 1.0±0.1 g/cm3 沸点 210.9±0.0 °C at 760 mmHg
分子式 C8H10O 熔点 22-23 °C(lit.)
MSDS 中文版 美版 闪点 85.6±7.2 °C
符号 GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
信号词 Danger

Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).

J. Med. Chem. 48 , 3269-79, (2005)

Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in the...

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspase activity by 50% (I50) and utilized these data to develop ...

Double salts of ionic-liquid-based surfactants in microextraction: application of their mixed hemimicelles as novel sorbents in magnetic-assisted micro-dispersive solid-phase extraction for the determination of phenols.

Anal. Bioanal. Chem 407 , 8753-64, (2015)

The use of mixed hemimicelles of ionic liquid (IL)-based surfactants in a magnetic-based micro-dispersive solid-phase extraction (m-μdSPE) approach is described. Not only is the symmetric monocationic IL-based surfactant 1,3-didodecylimidazolium bromide (C12C...

QSAR study on permeability of hydrophobic compounds with artificial membranes.

Bioorg. Med. Chem. 15 , 3756-67, (2007)

We previously reported a classical quantitative structure-activity relationship (QSAR) equation for permeability coefficients (P(app-pampa)) by parallel artificial membrane permeation assay (PAMPA) of structurally diverse compounds with simple physicochemical...

Analysis of phenolic compounds in the dissolved and suspended phases of Lake Balaton water by gas chromatography-tandem mass spectrometry.

Environ. Sci. Pollut. Res. Int. 22 , 11966-74, (2015)

As a novel approach to characterize the phenolic pollutants of Lake Balaton (Central Europe, western Hungary), 26 endocrine disrupting phenols (chlorophenols, nitrophenols, alkylphenols, triclosan, bisphenol-A) were quantified in dissolved and suspended parti...

Benzylic and aryl hydroxylations of m-xylene by o-xylene dioxygenase from Rhodococcus sp. strain DK17.

Appl. Microbiol. Biotechnol. 86(6) , 1841-7, (2010)

Escherichia coli cells expressing Rhodococcus DK17 o-xylene dioxygenase genes were used for bioconversion of m-xylene. Gas chromatography-mass spectrometry analysis of the oxidation products detected 3-methylbenzylalcohol and 2,4-dimethylphenol in the ratio 9...

Antimycoplasmal activity of dimethylphenols in a tracheal explant culture system.

Antimicrob. Agents Chemother. 18(2) , 243-8, (1980)

Mycoplasma pneumoniae induces pneumonia-like symptoms in hamsters and causes ciliostasis and cytonecrosis in hamster tracheal explants. 2,4-Dimethylphenol and, to a lesser extent, its 2,3-, 2,5-, and 2,6-dimethylphenol isomers protected tracheal explants from...

Metabolism and distribution of 2,4-dimethylphenol in rat.

Ecotoxicol. Environ. Saf. 6(1) , 35-40, (1982)

The concentration of 2,4-DMP was determined for several tissues of the rat by gas chromatographic methods after 6 hr constant intravenous infusion and after intravenous bolus injection. 2,4-DMP was distributed rapidly in the brain and liver. It has higher tis...

Comparison of the effect of phenol and its derivatives on protein and free radical formation in human erythrocytes (in vitro).

Blood Cells Mol. Dis. 39(3) , 238-44, (2007)

The effect of phenolic compounds: phenol, 2,4-dichlorophenol (2,4-DCP), 2,4-dimethylphenol (2,4-DMP) and catechol on human erythrocytes was studied. The level of fluorescent label - 6-carboxy-2',7'-dichlorodihydrofluorescein diacetate (H(2)DCFDA) oxidation by...

Catalase activity in human erythrocytes: effect of phenoxyherbicides and their metabolites.

Cell Biol. Int. 24(10) , 705-11, (2000)

The effects of exposure to different concentrations of phenoxyherbicides and their metabolites were studied in human erythrocytes, with particular attention to catalase (CAT-EC. 1.11.1. 6- hydrogen peroxide: hydrogen peroxide oxidoreductase). 4-chloro-2-methy...