α-氯醛糖
一般危化品
α-氯醛糖结构式
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常用名 | α-氯醛糖 | 英文名 | Chloralose |
|---|---|---|---|---|
| CAS号 | 15879-93-3 | 分子量 | 309.528 | |
| 密度 | 1.8±0.1 g/cm3 | 沸点 | 504.4±45.0 °C at 760 mmHg | |
| 分子式 | C8H11Cl3O6 | 熔点 | 178-182 °C | |
| MSDS | 中文版 美版 | 闪点 | 258.9±28.7 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Obesity depresses baroreflex control of renal sympathetic nerve activity and heart rate in Sprague Dawley rats: role of the renal innervation.
Acta Physiol. (Oxf.) 214 , 390-401, (2015) This study investigated the role of the renal innervation in arterial and cardiopulmonary baroreflex regulation of renal sympathetic nerve activity (RSNA) and heart rate (HR) in rats fed a high-fat diet to induce obesity.Rats received either a normal (12% kca... |
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Different anesthesia regimes modulate the functional connectivity outcome in mice.
Magn. Reson. Med. 72(4) , 1103-12, (2014) The use of resting-state functional MRI (rsfMRI) in preclinical research is expanding progressively, with the majority of resting-state imaging performed in anesthetized animals. Since anesthesia may change the physiology and, in particular, the neuronal acti... |
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Dexmedetomidine and regulation of splenic sympathetic nerve discharge in aged F344 rats.
Auton. Neurosci. 190 , 53-7, (2015) Sedatives influence the immune system and centrally-acting alpha2-adrenergic receptor agonists, including Dexmedetomidine (Dex), modulate sympathetic nerve discharge (SND). Because sedatives are used under medical conditions that include elderly patients, and... |
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The Effects of the Adenosine Receptor Antagonists on the Reverse of Cardiovascular Toxic Effects Induced by Citalopram In-Vivo Rat Model of Poisoning.
Balkan. Med. J. 32 , 303-8, (2015) Citalopram is a selective serotonin reuptake inhibitor that requires routine cardiac monitoring to prevent a toxic dose. Prolongation of the QT interval has been observed in acute citalopram poisoning. Our previous experimental study showed that citalopram ma... |
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Contribution of CCK1 receptors to cardiovascular and respiratory effects of cholecystokinin in anesthetized rats.
Neuropeptides 54 , 29-34, (2015) The study investigated the share of vagal input at infra- and supra-nodosal level and the contribution of CCK1 and CCK2 receptors to the cardiorespiratory responses produced by an intravenous injection of sulfated cholecystokinin octapeptide (CCK-8) in anesth... |
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Colokinetic effect of noradrenaline in the spinal defecation center: implication for motility disorders.
Sci. Rep. 5 , 12623, (2015) Chronic abdominal pain in irritable bowel syndrome (IBS) usually appears in combination with disturbed bowel habits, but the etiological relationship between these symptoms remains unclear. Noradrenaline is a major neurotransmitter controlling pain sensation ... |
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Dual blockade of endothelin action exacerbates up-regulated VEGF angiogenic signaling in the heart of lipopolysaccharide-induced endotoxemic rat model.
Life Sci. 118(2) , 364-9, (2015) Sepsis is a cluster of heterogeneous syndromes associated with progressive endotoxemic developments, ultimately leading to damage of multiple organs, including the heart. However, the pathogenesis of sepsis-induced myocardial dysfunction is still not fully un... |
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Role of neurotensin and opioid receptors in the cardiorespiratory effects of [Ile⁹]PK20, a novel antinociceptive chimeric peptide.
Eur. J. Pharm. Sci. 63 , 8-13, (2014) Ile(9)PK20 is a novel hybrid of opioid-neurotensin peptides synthesized from the C-terminal hexapeptide of neurotensin and endomorphin-2 pharmacophore. This chimeric compound shows potent central and peripheral antinociceptive activity in experimental animals... |
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NMDA receptor activation increases free radical production through nitric oxide and NOX2.
J. Neurosci. 29 , 2545-52, (2009) Reactive oxygen species (ROS) and nitric oxide (NO) participate in NMDA receptor signaling. However, the source(s) of the ROS and their role in the increase in cerebral blood flow (CBF) induced by NMDA receptor activation have not been firmly established. NAD... |
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Different effects of α-chloralose on spontaneous and evoked GABA release in rat hippocampal CA1 neurons
Brain Res. Bull. 85(3-4) , 180-8, (2011) Highlights ► Modulation of α-chloralose on extra- and intra-synaptic GABA A receptors. ► α-Chloralose dose dependently potentiates exogenous GABA-induced Cl − response. ► 10 μM α-Chloralose facilitates sIPSC frequency, and decreased failure rate of eIPSC. ► 3... |