D-α-羟基异戊酸
D-α-羟基异戊酸结构式
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常用名 | D-α-羟基异戊酸 | 英文名 | D-α-HYDROXYISOVALERIC ACID |
|---|---|---|---|---|
| CAS号 | 17407-56-6 | 分子量 | 118.131 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 237.6±13.0 °C at 760 mmHg | |
| 分子式 | C5H10O3 | 熔点 | 64-67ºC | |
| MSDS | 中文版 美版 | 闪点 | 111.8±16.3 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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α-Ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain
Brain Res. 1324 , 75-84, (2010) Patients affected by maple syrup urine disease (MSUD) present severe neurological symptoms and brain abnormalities, whose pathoiphysiology is poorly known. In the present study we investigated the in vitro effects of leucine (Leu), α-ketoisocaproic acid (KIC)... |
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Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
J. Biol. Chem. 282 , 23841-53, (2007) Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding ... |
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Enantiomeric separation and discrimination of 2-hydroxy acids as O-trifluoroacetylated (S)-(+)-3-methyl-2-butyl esters by achiral dual-capillary column gas chromatography.
J. Chromatogr. A. 874(1) , 91-100, (2000) An efficient method is described for the simultaneous enantiomeric separation of 18 different racemic 2-hydroxy acids for the determination of their absolute configurations. It involves the conversion of each enantiomer into a diastereomeric O-trifluoroacetyl... |
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Proton HR-MAS NMR spectroscopic characterization of metabolites in various human organ tissues: pancreas, brain and liver from trauma cases.
Physiol. Chem. Phys. Med. NMR 40 , 67-88, (2008) High-Resolution Magic Angle Spinning (HR-MAS) NMR has been employed to characterize various metabolites of human pancreas, liver and brain tissues from trauma cases. The potential usefulness of NMR in identifying the metabolites in human tissues has been expl... |
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Bacterial expression of catalytically active fragments of the multifunctional enzyme enniatin synthetase.
J. Mol. Biol. 243(1) , 116-22, (1994) Enniatin synthetase catalyzes the biosynthesis of N-methylated cyclohexadepsipeptides. The 347 kDa enzyme is encoded by the esyn1 gene of Fusarium scirpi and contains two domains (EA and EB) homologous to each other and to regions of other microbial peptide s... |
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Effects of birth asphyxia on urinary organic acid excretion.
Biol. Neonate 61(3) , 162-72, (1992) Using capillary gas chromatography-mass spectrometry, the effects of birth asphyxia on the urinary organic acid profile of term babies was investigated. Random urine samples were collected on days 1 and 8 from 19 babies with fetal distress, 19 with moderate b... |
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Disturbances of valine metabolism in patients with peroxisomal biogenesis disorders.
Adv. Exp. Med. Biol. 544 , 73-4, (2003)
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Two step derivatization for the analyses of organic, amino acids and glycines on filter paper plasma by GC-MS/SIM.
Arch. Pharm. Res. 30(3) , 387-95, (2007) A rapid dried-filter paper plasma-spot analytical method was developed to quantify organic acids, amino acids, and glycines simultaneously in a two-step derivatization procedure with good sensitivity and specificity. The new method involves a two-step trimeth... |
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Immunosuppressive effects of organic acids accumulating in patients with maple syrup urine disease.
J. Inherit. Metab. Dis. 18(2) , 165-8, (1995)
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Siderophore production by Proteus mirabilis.
Can. J. Microbiol. 30(8) , 1046-51, (1984) Studies on the isolation and characterization of Proteus mirabilis siderophores provided no evidence that these bacteria synthesize catechol- or hydroxamate-type siderophores. However, gas chromatograph analysis in conjunction with mass spectroscopy revealed ... |