2-氧代戊酸
2-氧代戊酸结构式
|
常用名 | 2-氧代戊酸 | 英文名 | 2-Oxovaleric acid |
|---|---|---|---|---|
| CAS号 | 1821-02-9 | 分子量 | 116.11500 | |
| 密度 | 1.110 g/mL at 20 °C(lit.) | 沸点 | 88-90 °C12 mm Hg(lit.) | |
| 分子式 | C5H8O3 | 熔点 | 7-9 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 94°C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Mosquito odorant receptor for DEET and methyl jasmonate.
Proc. Natl. Acad. Sci. U. S. A. 111(46) , 16592-7, (2014) Insect repellents are important prophylactic tools for travelers and populations living in endemic areas of malaria, dengue, encephalitis, and other vector-borne diseases. DEET (N,N-diethyl-3-methylbenzamide) is a 6-decade-old synthetic repellent, which is st... |
|
|
An RNA-seq screen of the Drosophila antenna identifies a transporter necessary for ammonia detection.
PLoS Genet. 10(11) , e1004810, (2014) Many insect vectors of disease detect their hosts through olfactory cues, and thus it is of great interest to understand better how odors are encoded. However, little is known about the molecular underpinnings that support the unique function of coeloconic se... |
|
|
Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues.
Bioorg. Med. Chem. 16 , 9975-83, (2008) We report the synthesis of (2E,5E)-4-oxoheptadienedioic acid and (2E)-4-oxoheptenedioic acid and evaluation of both diester and diacid analogues as inhibitors of bacterial dihydrodipicolinate synthase. Enzyme kinetic studies allowed the determination of secon... |
|
|
Chiral hydroxylation at the mononuclear nonheme Fe(II) center of 4-(S) hydroxymandelate synthase--a structure-activity relationship analysis.
PLoS ONE 8 , e68932, (2013) (S)-Hydroxymandelate synthase (Hms) is a nonheme Fe(II) dependent dioxygenase that catalyzes the oxidation of 4-hydroxyphenylpyruvate to (S)-4-hydroxymandelate by molecular oxygen. In this work, the substrate promiscuity of Hms is characterized in order to as... |
|
|
Cloning and overexpression of ketopantoic acid reductase gene from Stenotrophomonas maltophilia and its application to stereospecific production of D-pantoic acid.
Appl. Microbiol. Biotechnol. 93(4) , 1619-25, (2012) Ketopantoic acid (KPA) reductase catalyzes the stereospecific reduction of ketopantoic acid to D-pantoic acid. Based on the N-terminal amino acid sequence of KPA reductase from Stenotrophomonas maltophilia 845, the KPA reductase gene was cloned from S. maltop... |
|
|
Direct inhibition of the pancreatic beta-cell ATP-regulated potassium channel by alpha-ketoisocaproate.
J. Biol. Chem. 273(23) , 14113-8, (1998) The ATP-regulated potassium (KATP) channel plays an essential role in the control of insulin release from the pancreatic beta-cell. In the present study we have used the patch-clamp technique to study the direct effects of alpha-ketoisocaproate on the KATP ch... |
|
|
Threonine 246 at the active site of the L-lactate dehydrogenase of Bacillus stearothermophilus is important for catalysis but not for substrate binding.
Biochemistry 32(47) , 12730-5, (1993) Threonine 246 is an active site residue that is conserved in all known L-lactate dehydrogenase (LDH; EC 1.1.1.27) sequences. In order to investigate the role of Thr246 in Bacillus stearothermophilus LDH, this residue was altered by site-directed mutagenesis t... |
|
|
High-performance liquid chromatographic determination of alpha-keto acids in human serum and urine using 1,2-diamino-4,5-methylenedioxybenzene as a precolumn fluorescence derivatization reagent.
J. Chromatogr. A. 430(2) , 223-31, (1988) A simple and highly sensitive high-performance liquid chromatographic (HPLC) method for the determination of alpha-keto acids in human serum and urine is described. In an acidic solution, twelve species of alpha-keto acids examined were converted by reaction ... |
|
|
Human sweat and 2-oxopentanoic acid elicit a landing response from Anopheles gambiae.
Med. Vet. Entomol. 14(2) , 195-200, (2000) A wind tunnel bioassay and video to observe mosquitoes landing on heated glass cylinders were used to test sweat and some derivatives for responses of Anopheles gambiae Giles (Diptera: Culicidae), a highly anthropophilic African species of malaria vector. Fil... |
|
|
Gas chromatographic-mass spectrometric screening for organic acidemias using dried urine filter paper: determination of alpha-ketoacids.
J. Chromatogr. B. Biomed. Sci. Appl. 758(1) , 87-94, (2001) There are several organic acid disorders that require information on alpha-ketoacids, such as maple syrup urine disease or alpha-ketoadipic acidemia. The recovery, stability and diagnostic availability of alpha-ketoacids in dried urine filter paper analyzed b... |