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N-叔丁基-十氢异喹啉-3(S)-甲酰胺

N-叔丁基-十氢异喹啉-3(S)-甲酰胺结构式
N-叔丁基-十氢异喹啉-3(S)-甲酰胺结构式
品牌特惠专场
常用名 N-叔丁基-十氢异喹啉-3(S)-甲酰胺 英文名 (S)-N-t-butyl decahydro-3-iso-quinolinecarboxamide
CAS号 136465-81-1 分子量 238.369
密度 1.0±0.1 g/cm3 沸点 401.5±24.0 °C at 760 mmHg
分子式 C14H26N2O 熔点 112-115ºC
MSDS 中文版 美版 闪点 146.7±23.0 °C
符号 GHS05 GHS07
GHS05, GHS07
信号词 Danger

A series of potent HIV-1 protease inhibitors containing a hydroxyethyl secondary amine transition state isostere: synthesis, enzyme inhibition, and antiviral activity.

J. Med. Chem. 35 , 2525, (1992)

A series of HIV-1 protease inhibitors containing a novel hydroxyethyl secondary amine transition state isostere has been synthesized. The compounds exhibit a strong preference for the (R) stereochemistry at the transition state hydroxyl group. Molecular model...

Trova, M.P. et al.

Bioorg. Med. Chem. Lett. 3 , 1595, (1993)