Roquefortine C
Roquefortine C结构式
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常用名 | Roquefortine C | 英文名 | isoroquefortine C |
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| CAS号 | 58735-64-1 | 分子量 | 389.450 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 768.3±60.0 °C at 760 mmHg | |
| 分子式 | C22H23N5O2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 418.4±32.9 °C |
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Novel key metabolites reveal further branching of the roquefortine/meleagrin biosynthetic pathway.
J. Biol. Chem. 288(52) , 37289-95, (2013) Metabolic profiling and structural elucidation of novel secondary metabolites obtained from derived deletion strains of the filamentous fungus Penicillium chrysogenum were used to reassign various previously ascribed synthetase genes of the roquefortine/melea... |
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Determination of selected mycotoxins in mould cheeses with liquid chromatography coupled to tandem with mass spectrometry.
Food Addit. Contam. 22(5) , 449-56, (2005) A simple and feasible method is described for analysing nine mycotoxins in cheese matrix. The method involves liquid extraction followed by high performance liquid chromatographic separation and mass spectrometric detection of the analytes, and allows the det... |
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A single cluster of coregulated genes encodes the biosynthesis of the mycotoxins roquefortine C and meleagrin in Penicillium chrysogenum.
Chem. Biol. 18(11) , 1499-512, (2011) A single gene cluster of Penicillium chrysogenum contains genes involved in the biosynthesis and secretion of the mycotoxins roquefortine C and meleagrin. Five of these genes have been silenced by RNAi. Pc21g15480 (rds) encodes a nonribosomal cyclodipeptide s... |
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Roquefortine/oxaline biosynthesis pathway metabolites in Penicillium ser. Corymbifera: in planta production and implications for competitive fitness.
J. Chem. Ecol. 31(10) , 2373-90, (2005) Three strains of each of the seven taxa comprising the Penicillium series Corymbifera were surveyed by direct injection mass spectrometry (MS) and liquid chromatography-MS for the production of terrestric acid and roquefortine/oxaline biosynthesis pathway met... |
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LC-MS/MS screen for penitrem A and roquefortine C in serum and urine samples.
Anal. Chem. 78(13) , 4624-9, (2006) A rapid LC-MS/MS method, using a triple quadrupole/linear ion trap mass spectrometer, was developed for determination of penitrem A and roquefortine C in serum and urine samples. Penitrem A and roquefortine C were extracted from samples with methylene chlorid... |
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Morphological, molecular, and mycotoxigenic identification of dominant filamentous fungi from moldy civil cheese.
J. Food Prot. 75(11) , 2045-9, (2012) Moldy Civil is a mold-ripened variety of cheese produced mainly in eastern Turkey. This cheese is produced with Civil cheese and whey curd cheese (Lor). Civil cheese has had a geographical presence since 2009 and is manufactured with skim milk. In the product... |
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Using roquefortine C as a biomarker for penitrem A intoxication.
J. Vet. Diagn. Invest. 21(2) , 237-9, (2009) Penitrem A is a well-recognized tremorgenic mycotoxin produced by several Penicillium spp. However, most natural cases of penitrem A intoxication have been associated with Penicillium crustosum. Another Penicillium sp., Penicillium roqueforti, is used for the... |
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Mycotoxin-forming ability of two Penicillium roqueforti strains in blue moldy tulum cheese ripened at various temperatures.
J. Food Prot. 67(3) , 533-5, (2004) Isolated and identified toxigenic and nontoxigenic Penicillium roqueforti (PR) strains from moldy tulum cheeses were inoculated into tulum cheeses made in the laboratory and ripened at 5 and 12 degrees C. Mycotoxin (patulin, penicillic acid, PR toxin, and roq... |
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The heterotrimeric Galpha protein pga1 regulates biosynthesis of penicillin, chrysogenin and roquefortine in Penicillium chrysogenum.
Microbiology 154(Pt 11) , 3567-78, (2008) We have studied the role of the pga1 gene of Penicillium chrysogenum, encoding the alpha subunit of a heterotrimeric G protein, in secondary metabolite production. The dominant activating pga1(G42R) mutation caused an increase in the production of the three s... |
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The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes.
Mycopathologia 158(3) , 317-24, (2004) The in vitro effect of each of the Penicillium mycotoxins citrinin (CIT), cyclopiazonic acid (CPA), ochratoxin A (OTA), patulin (PAT), penicillic acid (PIA) and roquefortine C (RQC) on mitogen induced lymphocyte proliferation was determined using purified lym... |