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天青A曙红

天青A曙红结构式
天青A曙红结构式
品牌特惠专场
常用名 天青A曙红 英文名 Azure A eosinate
CAS号 62298-43-5 分子量 291.79900
密度 N/A 沸点 N/A
分子式 C14H14ClN3S 熔点 N/A
MSDS 美版 闪点 N/A

A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.

Bioorg. Med. Chem. Lett. 19 , 4952-7, (2009)

Aggregated amyloid-beta (Abeta) peptide is implicated in the pathology of Alzheimer's disease. In vitro and in vivo, these aggregates are found in a variety of morphologies, including globular oligomers and linear fibrils, which possess distinct biological ac...

Ligand polarizability contributes to tau fibril binding affinity.

Bioorg. Med. Chem. 19 , 5147-54, (2011)

Whole brain imaging of tau-bearing neurofibrillary lesions has the potential to improve the premortem diagnosis and staging of Alzheimer's disease. Diverse compounds with high affinity for tau aggregates have been reported from high-throughput screens, but th...